Evidence map›Paper›PMID 34484243›Full record

ArticleFrontiers in immunology2021

A Bibliometric Analysis of Pyroptosis From 2001 to 2021.

Dan Ma, Bin Yang, Baoyi Guan, Luxia Song, Qiyu Liu, Yixuan Fan, Lin Zhao, Tongxin Wang, Zihao Zhang, Zhuye Gao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
147citing papers in PubMed, 15 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

147 citing papers in PubMed, 15 syntheses or guidelines pooled it, 206 citations in OpenAlex.

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  12. MXene nanomaterials in biomedicine: A bibliometric perspective.Frontiers in bioengineering and biotechnology · 2023
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  16. Article
  17. Article
  18. Challenges and Opportunities in Cronkhite-Canada Syndrome Research: A Bibliometric Analysis Based on the Web of Science Core Collection.Medical science monitor : international medical journal of experimental and clinical research · 2026
    Article
  19. A bibliometric analysis of global research trends in autophagy and glioblastomas.Naunyn-Schmiedeberg's archives of pharmacology · 2026
    Article
  20. Article

87 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Dan MaXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Bin YangXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Baoyi GuanXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Luxia SongGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Qiyu LiuGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Yixuan FanGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Lin ZhaoGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Tongxin WangGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Zihao ZhangGraduate School, Beijing University of Chinese Medicine, Beijing, China.
Zhuye GaoXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Siming LiXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Hao XuXiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Beijing University of Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNXiyuan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pyroptosis is a new programmed cell death discovered in recent years. Pyroptosis plays an important role in various diseases. Nevertheless, there are few bibliometric analysis systematically studies this field. We aimed to visualize the research hotspots and trends of pyroptosis using a bibliometric analysis to help understand the future development of basic and clinical research. Methods: The articles and reviews regarding pyroptosis were culled from Web of Science Core Collection. Countries, institutions, authors, references and keywords in this field were visually analyzed by using CtieSpace and VOSviewer software. Results: A total of 2845 articles and reviews were included. The number of articles regarding pyroptosis significantly increased yearly. These publications mainly come from 70 countries led by China and the USA and 418 institutions. We identified 605 authors, among which Thirumaladevi Kanneganti had the most significant number of articles, and Shi JJ was co-cited most often. Conclusion: Research on the pyroptosis is flourishing. Cooperation and exchanges between countries and institutions must be strengthened in the future. The related pathway mechanism of pyroptosis, the relationship between pyroptosis and other types of programmed cell deaths as well as the role of pyroptosis in various diseases have been the focus of current research and developmental trends in the future research.

Indexed as

PyroptosisAllergy and ImmunologyAnimalsAuthorshipBibliometricsBiomedical ResearchDatabases, BibliographicData MiningDiffusion of InnovationHumansImmune SystemPeriodicals as TopicSignal TransductioncaspaseCiteSpaceGSDMDNLRP3programmed cell deathpyroptosisVOSviewer

Identifiers

PMID34484243
PMCPMC8416445
OpenAlexW3194094059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.