Evidence map›Paper›PMID 34484213›Full record

ArticleFrontiers in immunology2021

Association of HLA-DPA1, HLA-DPB1, and HLA-DQB1 Alleles With the Long-Term and Booster Immune Responses of Young Adults Vaccinated Against the Hepatitis B Virus as Neonates.

Wen-Chang Wang, Yu-Shiang Lin, Yin-Fan Chang, Chih-Ching Yeh, Chien-Tien Su, Jin-Shang Wu, Fu-Hsiung Su

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

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  9. The genetic variantFrontiers in oncology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Wen-Chang WangThe Ph.D. Program for Translational Medicine, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Yu-Shiang LinSchool of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Yin-Fan ChangDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chih-Ching YehCancer Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Chien-Tien SuSchool of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan.
Jin-Shang WuDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Fu-Hsiung SuDepartment of Family Medicine, Cardinal Tien Hospital, Fu Jen Catholic University, New Taipei City, Taiwan.
National Cheng Kung University Hospital · TWChina Medical University · TWFu Jen Catholic University · TWTaipei Medical University · TWTaipei Medical University Hospital · TWWan Fang Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neonatal hepatitis B vaccination (HBVac) was implemented 35 years ago in Taiwan, but many vaccinees exhibit inadequate long-term vaccine-induced seroprotective hepatitis B surface antibody (anti-HBs) levels. We investigated the association of the human leukocyte antigen (HLA) alleles (DPA1, DPB1, DQA1, and DQB1) with the long-term immunological response to the neonatal HBVac and adolescent booster HBVac in a Taiwanese cohort. We divided 281 Han students (median age 22, age range 17-29 years) into the following groups: (1) Group A (

Indexed as

VaccinationAdolescentAdultAllelesCase-Control StudiesFemaleHaplotypesHepatitis B VaccinesHLA-DP alpha-ChainsHLA-DP beta-ChainsHLA-DQ beta-ChainsHumansImmunization, SecondaryInfant, NewbornMaleYoung AdultHepatitis B VaccinesHLA-DPA1 antigenHLA-DP alpha-ChainsHLA-DPB1 antigenHLA-DP beta-ChainsHLA-DQB1 antigenHLA-DQ beta-ChainsboosterHBV serologyhepatitis B vaccinehuman leukocyte antigenimmunogenic response

Identifiers

PMID34484213
PMCPMC8416438
OpenAlexW3193506986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.