Evidence map›Paper›PMID 34484183›Full record

ArticleFrontiers in immunology2021

The Immunomodulatory Effect of Triptolide on Mesenchymal Stromal Cells.

Haiping He, Atsuko Takahashi, Takeo Mukai, Akiko Hori, Miwako Narita, Arinobu Tojo, Tonghua Yang, Tokiko Nagamura-Inoue

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Haiping HeDepartment of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Atsuko TakahashiDepartment of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Takeo MukaiDepartment of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Akiko HoriDepartment of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Miwako NaritaLaboratory of Hematology and Oncology, School of Health Science, Niigata University Faculty of Medicine, Niigata, Japan.
Arinobu TojoDivision of Molecular Therapy, Center for Advanced Medical Research, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Tonghua YangDepartment of Hematology, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, China.
Tokiko Nagamura-InoueDepartment of Cell Processing and Transfusion, The Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
The University of Tokyo · JPFirst People's Hospital of Yunnan Province · CNKunming University of Science and Technology · CNNiigata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stromal cells (MSCs) are known to have immunosuppressive ability and have been used in clinical treatment of acute graft-

Indexed as

B7-H1 AntigenCell ProliferationCoculture TechniquesDiterpenesEpoxy CompoundsHumansImmunomodulationImmunosuppression TherapyIndoleamine-Pyrrole 2,3,-DioxygenaseInterferon-gammaMesenchymal Stem CellsPhenanthrenesT-LymphocytesUmbilical CordB7-H1 AntigenDiterpenesEpoxy CompoundsIndoleamine-Pyrrole 2,3,-DioxygenaseInterferon-gammaPhenanthrenestriptolideimmunosuppressionmesenchymal stromal cellsPD-L1triptolideumbilical cord

Identifiers

PMID34484183
PMCPMC8415460
OpenAlexW3195596680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.