Evidence map›Paper›PMID 34484177›Full record

ArticleFrontiers in immunology2021

Neutrophils Affect IL-33 Processing in Response to the Respiratory Allergen

Sharon Van Nevel, Judith van Ovost, Gabriele Holtappels, Natalie De Ruyck, Nan Zhang, Harald Braun, Tania Maes, Claus Bachert, Olga Krysko

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sharon Van NevelUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Judith van OvostUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Gabriele HoltappelsUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Natalie De RuyckUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Nan ZhangUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Harald BraunUnit for Structural Biology, VIB-UGent Center for Inflammation Research, Ghent, Belgium.
Tania MaesDepartment of Respiratory Medicine, Department of Internal Medicine, Ghent University, Ghent, Belgium.
Claus BachertUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Olga KryskoUpper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
Ghent University · BEKarolinska University Hospital · SEVIB-UGent Center for Inflammation Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Future precision medicine requires further clarifying the mechanisms of inflammation in the severe endotypes of chronic airway diseases such as asthma and chronic rhinosinusitis (CRS). The presence of neutrophils in the airways is often associated with severe airway inflammation, while their precise contribution to the severe inflammation is largely unknown. We aimed to study the role of neutrophils in BALB/c and C57BL/6 mice exposed to

Indexed as

Immunity, InnateAllergensAlternariaAlternariosisAnimalsAsthmaDisease Models, AnimalFemaleInterleukin-33LungMiceMice, Inbred BALB CMice, Inbred C57BLNeutrophilsRhinitisSinusitisAllergensIl33 protein, mouseInterleukin-33allergyasthmaelastaseproteasetype 2 inflammation

Identifiers

PMID34484177
PMCPMC8416032
OpenAlexW3194609896

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.