Evidence map›Paper›PMID 34484172›Full record

ReviewFrontiers in microbiology2021

Adaptive Laboratory Evolution of Microalgae: A Review of the Regulation of Growth, Stress Resistance, Metabolic Processes, and Biodegradation of Pollutants.

Bo Zhang, Jiangyue Wu, Fanping Meng

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Adaptive Laboratory Evolution inMicroorganisms · 2026
    Review
  3. Review
  4. Response of aBiology · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Marine drugs · 2026
    Review
  9. Article
  10. Review
  11. Progress and challenges in CRISPR/Cas applications in microalgae.Journal of microbiology (Seoul, Korea) · 2025
    Review
  12. Article
  13. Review
  14. Article
  15. An efficient co-culture ofFrontiers in microbiology · 2024
    Article
  16. Review
  17. A synthetic biology approach for the treatment of pollutants with microalgae.Frontiers in bioengineering and biotechnology · 2024
    Review
  18. Experimental evolution for cell biology.Trends in cell biology · 2023
    Review
  19. The Influence of Elevated COPlants (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bo ZhangKey Laboratory of Marine Environment and Ecology, Ministry of Education, Ocean University of China, Qingdao, China.
Jiangyue WuNational Marine Hazard Mitigation Service, Ministry of Natural Resource of the People's Republic of China, Beijing, China.
Fanping MengKey Laboratory of Marine Environment and Ecology, Ministry of Education, Ocean University of China, Qingdao, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptive laboratory evolution (ALE) experiments are a serviceable method for the industrial utilization of the microalgae, which can improve the phenotype, performance, and stability of microalgae to obtain strains containing beneficial mutations. In this article, we reviewed the research into the microalgae ALE test and assessed the improvement of microalgae growth, tolerance, metabolism, and substrate utilization by ALE. In addition, the principles of ALE and the key factors of experimental design, as well as the issues and drawbacks of the microalgae ALE method were discussed. In general, improving the efficiency of ALE and verifying the stability of ALE resulting strains are the primary problems that need to be solved in future research, making it a promising method for the application of microalgae biotechnology.

Indexed as

adaptive laboratory evolutionbiodegradation of pollutantsgrowthmetabolic regulationmicroalgaestress resistance

Identifiers

PMID34484172
PMCPMC8416440

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.