Evidence map›Paper›PMID 34484131›Full record

ArticleFrontiers in microbiology2021

Delivery Mode Affects Intestinal Microbial Composition and the Development of Intestinal Epithelial Cells.

Linzheng Lyu, Xiaohong Zhou, Meng Zhang, Li Liu, Haiyue Niu, Jiliang Zhang, Shiwei Chen, Pimin Gong, Shilong Jiang, Jiancun Pan and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Linzheng LyuSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Xiaohong ZhouQingdao Central Hospital, Qingdao, China.
Meng ZhangThe Third Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Li LiuThe Third Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Haiyue NiuSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Jiliang ZhangSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Shiwei ChenSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Pimin GongCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Shilong JiangHeilongjiang Feihe Dairy Co., Ltd., Beijing, China.
Jiancun PanHeilongjiang Feihe Dairy Co., Ltd., Beijing, China.
Yuanyuan LiHeilongjiang Feihe Dairy Co., Ltd., Beijing, China.
Xue HanSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Dayou ChengSchool of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, China.
Lanwei ZhangCollege of Food Science and Engineering, Ocean University of China, Qingdao, China.
Harbin Institute of Technology · CNFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine · CNOcean University of China · CNQingdao Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe infant's intestine contains diverse microbiota, which play an important role in an infant's health.

objectiveThis study aimed to analyze the different intestinal microbiota and their function in two delivery modes [vaginal delivery and cesarean section (C-section)] and to investigate the proprieties of bacteria associated with vaginal delivery on the development of intestinal epithelial cells in rat pups. MATERIALS AND

methodsWe evaluated the intestinal microbial diversity of the stool samples of 51 infants of subjects who underwent vaginal delivery and C-section by sequencing the V4 regions of the 16S rRNA gene and predicted the function of the microbiotas. The infant stool microbiota in the vaginal delivery group was associated with the digestive system and cell growth and death, whereas that of the C-section group was associated with membrane transport. Then, we isolated the strains based on function prediction.

resultsA total of 95 strains were isolated in the vaginal delivery group.

conclusionThe results of this study indicate an apparent difference in the bacterial composition of the stool samples collected from infants of the two delivery modes. By analyzing and screening the bacteria in infant stool samples, we found that one strain, i.e.,

Indexed as

bacterial screeningcell proliferationdelivery modesinfant intestinal epithelial cellsintestinal microbiota

Identifiers

PMID34484131
PMCPMC8414977
OpenAlexW3193593902

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.