Evidence map›Paper›PMID 34484128›Full record

ReviewFrontiers in endocrinology2021

COVID-19 and Obesity: Role of Ectopic Visceral and Epicardial Adipose Tissues in Myocardial Injury.

Adèle Lasbleiz, Bénédicte Gaborit, Astrid Soghomonian, Axel Bartoli, Patricia Ancel, Alexis Jacquier, Anne Dutour

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Fulminant Myocarditis with SARS-CoV-2 Infection: A Narrative Review from the Case Studies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Obesity and COVID-19: What are the Consequences?Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2022
    Review
  16. Article
  17. Review
  18. Editorial: Obesity, metabolic phenotypes and COVID-19.Metabolism: clinical and experimental · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Adèle LasbleizDepartment of Endocrinology, Metabolic Diseases and Nutrition, Pôle ENDO, APHM, Marseille, France.
Bénédicte GaboritDepartment of Endocrinology, Metabolic Diseases and Nutrition, Pôle ENDO, APHM, Marseille, France.
Astrid SoghomonianDepartment of Endocrinology, Metabolic Diseases and Nutrition, Pôle ENDO, APHM, Marseille, France.
Axel BartoliAix Marseille Univ, CNRS, CRMBM, Marseille, France.
Patricia AncelAix Marseille Univ, INSERM, INRAE, C2VN, Marseille, France.
Alexis JacquierAix Marseille Univ, CNRS, CRMBM, Marseille, France.
Anne DutourDepartment of Endocrinology, Metabolic Diseases and Nutrition, Pôle ENDO, APHM, Marseille, France.
Centre de Résonance Magnétique Biologique et Médicale · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRAix-Marseille Université · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In March 2020, the WHO declared coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a global pandemic. Obesity was soon identified as a risk factor for poor prognosis, with an increased risk of intensive care admissions and mechanical ventilation, but also of adverse cardiovascular events. Obesity is associated with adipose tissue, chronic low-grade inflammation, and immune dysregulation with hypertrophy and hyperplasia of adipocytes and overexpression of pro-inflammatory cytokines. However, to implement appropriate therapeutic strategies, exact mechanisms must be clarified. The role of white visceral adipose tissue, increased in individuals with obesity, seems important, as a viral reservoir for SARS-CoV-2

Indexed as

Adipose TissueAngiotensin-Converting Enzyme 2CardiomyopathiesCOVID-19Heart DiseasesHumansInflammationIntra-Abdominal FatObesityPericardiumPrognosisSARS-CoV-2Serine EndopeptidasesACE2 protein, humanAngiotensin-Converting Enzyme 2Serine EndopeptidasesTMPRSS2 protein, humanadipose tissuecardiac injuryCOVID-19ectopic fatepicardial adipose tissueimmunityinflammationobesity

Identifiers

PMID34484128
PMCPMC8415546
OpenAlexW3196048591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.