Evidence map›Paper›PMID 34483963›Full record

SynthesisFrontiers in physiology2021

Correlation Between Soluble Klotho and Vascular Calcification in Chronic Kidney Disease: A Meta-Analysis and Systematic Review.

QiFeng Liu, LiXia Yu, XiaoYa Yin, JianMing Ye, ShaSha Li

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07654231 (Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07654231 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD: A Pilot Randomized Open-Label Trial (RESOLVE-CKD Trial)

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2026 to 2027Enrolled60ConditionsChronic Kidney Disease Mineral and Bone Disorder, Hypertension, Diabetes, DyslipidemiaArmsLow-dose Colchicine at 0.5mg daily, Usual Care
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  5. Review
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  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

QiFeng LiuDepartment of Nephrology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
LiXia YuDepartment of Nephrology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
XiaoYa YinDepartment of Nephrology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
JianMing YeDepartment of Nephrology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
ShaSha LiClinical Research & Lab Centre, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
Jiangsu University · CNFirst People's Hospital of Kunshan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkerchronic kidney dieasemanagementsKlothovascular calcifcation

Identifiers

PMID34483963
PMCPMC8414804
OpenAlexW3195278723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.