Evidence map›Paper›PMID 34483911›Full record

ArticleFrontiers in pharmacology2021

Effect of Two Unique Nanoparticle Formulations on the Efficacy of a Broadly Protective Vaccine Against

Debaki R Howlader, Sayan Das, Ti Lu, Gang Hu, David J Varisco, Zackary K Dietz, Sierra P Walton, Siva Sai Kumar Ratnakaram, Francesca M Gardner, Robert K Ernst and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. International journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Vaccines · 2022
    Review
  18. Article
  19. Detection ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Debaki R HowladerDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Sayan DasDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Ti LuDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Gang HuDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
David J VariscoDepartment of Microbial Pathogenesis, University of Maryland, Baltimore, MD, United States.
Zackary K DietzDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Sierra P WaltonDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Siva Sai Kumar RatnakaramDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Francesca M GardnerDepartment of Microbial Pathogenesis, University of Maryland, Baltimore, MD, United States.
Robert K ErnstDepartment of Microbial Pathogenesis, University of Maryland, Baltimore, MD, United States.
William D PickingDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
Wendy L PickingDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, United States.
University of Kansas · USUniversity of Maryland, Baltimore · US

Funding

Vaccines to counter emerging antibiotic resistance (R01AI138970)R01AI138970 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI PICKING, WENDY L. · 2018 to 2022
$6.0M
Development of a broadly protective subunit vaccine against Pseudomonas aeruginosaR21AI140701 · NIAID · UNIVERSITY OF KANSAS LAWRENCE · PI PICKING, WENDY L. · 2018 to 2019
$427k
NIAID NIH HHS R01 AI138970NIAID NIH HHS R21 AI140701
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

IL-17L-PaFnanoparticle vaccineopsonophagocytosisprotein formulationspseudomonasT3SS vaccine

Identifiers

PMID34483911
PMCPMC8416447
OpenAlexW3193300404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.