ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021
Alterations of Ocular Surface Parameters in Type 2 Diabetic Patients.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tear function in patients with diabetes mellitus: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Tear Film Alterations in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2025Review
- Ocular surface changes following vitreoretinal procedures.Indian journal of ophthalmology · 2023Review
- Alterations of ocular surface parameters in patients with obstructive sleep apnea syndrome.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of the study was to evaluate the changes in the ocular surface parameters of type 2 diabetic patients.
methodsThis study is a cross-sectional observational study. It included 76 eyes of 38 patients with type 2 diabetes and 183 eyes of 92 non-diabetic controls. The diabetic subjects were divided into two groups based on diabetic duration. Ocular surface parameters were assessed for all participants.
resultsThe diabetic group had a significantly thinner lipid layer thickness (LLT) (p = 0.008) than non-diabetic controls. LLT in the subgroup with diabetic duration ≥10 years was significantly thinner than that in the subgroup with diabetic duration <10 years (p = 0.006). Multivariate linear regression analysis showed that LLT was associated with the duration of diabetes (β = -1.497, p = 0.009) and Schirmer I test (SIT) score (β = 0.852, p = 0.04) in diabetic. Diabetic duration was significantly negatively associated with LLT (β = -0.062, p = 0.004) and significantly positively associated with ocular surface disease index (OSDI) (β = 0.087, p = 0.039).
conclusionDiabetic patients exhibit significantly reduced LLT and this trend becomes more pronounced with increased duration of diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.