ArticleBritish journal of cancer2021
Trajectories of alcohol consumption during life and the risk of developing breast cancer.
Article in British journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Adolescent Dietary Intake and Breast Cancer in Adulthood: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- Effectiveness of the Components of a Digital Multiple Health Behavior Intervention Among University Students (Buddy): Factorial Randomized Trial.Journal of medical Internet research · 2026Trial
- Lifetime Drinking Patterns Shape Awareness of Alcohol-Related Chronic Disease Risks in U.S. Adults: Findings From the National Alcohol Survey.Journal of studies on alcohol and drugs · 2026Article
- Factors Associated With Alcohol Intake in Patients With Newly Diagnosed Breast Cancer.Cancer medicine · 2026Article
- Alcohol-related health risks, cancer and government drinking guidelines: Views of adults at midlife in Aotearoa New Zealand.Journal of health psychology · 2026Article
- Associations of alcohol consumption with expression of CD44, CD24, and ALDH1A1 stem cell markers in benign breast biopsy samples.Cancer causes & control : CCC · 2025Article
- Alcohol consumption trajectories and risk of breast cancer among postmenopausal women: a Danish cohort study.European journal of epidemiology · 2024Article
- Article
- Trajectories of long-term exposure to PCB153 and Benzo[a]pyrene (BaP) air pollution and risk of breast cancer.Environmental health : a global access science source · 2024Article
- Global burden and attributable risk factors of breast cancer in young women: historical trends from 1990 to 2019 and forecasts to 2030 by sociodemographic index regions and countries.Journal of global health · 2024Article
- Temporal patterns of breast cancer incidence, mortality, disability-adjusted life years and risk factors in 12 South American Countries, 1990-2019: an examination using estimates from the global burden of disease 2019 study.Breast cancer research and treatment · 2023Article
- Year-round breast cancer awareness: Empowering young women in the fight against breast cancer.The Indian journal of medical research · 2023Article
- Developing a Women's Thought Collective methodology for health research: The roles and responsibilities of researchers in the reflexive co-production of knowledge.Health expectations : an international journal of public participation in health care and health policy · 2023Article
- Personalized Breast Cancer Screening: A Risk Prediction Model Based on Women Attending BreastScreen Norway.Cancers · 2023Article
- Family economic trajectories and body mass index in Indonesia: Evidence from the Indonesian Family Life Surveys 2 to 5.Preventive medicine reports · 2023Article
- Factors associated with public awareness of the relationship between alcohol use and breast cancer risk.BMC public health · 2023Article
- Alcohol and breast cancer.Pharmacological reports : PR · 2023Review
- Trajectories of alcohol consumption in relation to all-cause mortality in patients with cardiovascular disease: a 35-year prospective cohort study.Addiction (Abingdon, England) · 2022Article
- Article
Corrections and comments
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Authors and funding
23 authors at 17 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether there are lifetime points of greater sensitivity to the deleterious effects of alcohol intake on the breasts remains inconclusive.
objectiveTo compare the influence of distinctive trajectories of alcohol consumption throughout a woman's life on development of breast cancer (BC).
methods1278 confirmed invasive BC cases and matched (by age and residence) controls from the Epi-GEICAM study (Spain) were used. The novel group-based trajectory modelling was used to identify different alcohol consumption trajectories throughout women's lifetime.
resultsFour alcohol trajectories were identified. The first comprised women (45%) with low alcohol consumption (<5 g/day) throughout their life. The second included those (33%) who gradually moved from a low alcohol consumption in adolescence to a moderate in adulthood (5 to <15 g/day), never having a high consumption; and oppositely, women in the third trajectory (16%) moved from moderate consumption in adolescence, to a lower consumption in adulthood. Women in the fourth (6%) moved from a moderate alcohol consumption in adolescence to the highest consumption in adulthood (≥15 g/day), never having a low alcohol consumption. Comparing with the first trajectory, the fourth doubled BC risk (OR 2.19; 95% CI 1.27, 3.77), followed by the third (OR 1.44; 0.96, 2.16) and ultimately by the second trajectory (OR 1.17; 0.86, 1.58). The magnitude of BC risk was greater in postmenopausal women, especially in those with underweight or normal weight. When alcohol consumption was independently examined at each life stage, ≥15 g/day of alcohol consumption in adolescence was strongly associated with BC risk followed by consumption in adulthood.
conclusionsThe greater the alcohol consumption accumulated throughout life, the greater the risk of BC, especially in postmenopausal women. Alcohol consumption during adolescence may particularly influence BC risk.
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Registered trials
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