Evidence map›Paper›PMID 34482705›Full record

ArticleJournal of the American Heart Association2021

Simultaneous Pulmonary Artery Pressure and Left Ventricle Stroke Volume Assessment Predicts Adverse Events in Patients With Pulmonary Embolism.

Hayaan Kamran, Essa H Hariri, Jean-Pierre Iskandar, Aditya Sahai, Ihab Haddadin, Serge C Harb, Joseph Campbell, Leben Tefera, Joseph M Delehanty, Gustavo A Heresi and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hayaan KamranDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.ORCID 0000-0003-3865-677X
Essa H HaririDepartment of Medicine Cleveland Clinic Foundation Cleveland OH.
Jean-Pierre IskandarDepartment of Medicine Cleveland Clinic Foundation Cleveland OH.
Aditya SahaiDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.ORCID 0000-0003-1691-9604
Ihab HaddadinDepartment of Radiology Cleveland Clinic Foundation Cleveland OH.
Serge C HarbDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.
Joseph CampbellDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.
Leben TeferaDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.ORCID 0000-0001-9640-6774
Joseph M DelehantyDivision of Cardiology Department of Medicine University of Rochester Medical Center Rochester NY.
Gustavo A HeresiDepartment of Pulmonary and Critical Care Medicine Respiratory InstituteCleveland Clinic Foundation Cleveland OH.
John R BartholomewDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.
Scott J CameronDepartment of Cardiovascular Medicine Heart Vascular and Thoracic InstituteCleveland Clinic Foundation Cleveland OH.ORCID 0000-0002-9616-1540

Funding

Platelets as Biosensors and Mediators of Aortic Aneurysm GrowthR01HL158801 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI CAMERON, SCOTT JAMES · 2021 to 2025
$2.5M
Platelet ERK5 regulates myocardial infarct expansionK08HL128856 · NHLBI · UNIVERSITY OF ROCHESTER · PI CAMERON, SCOTT JAMES · 2016 to 2020
$775k
NHLBI NIH HHS K08 HL128856NHLBI NIH HHS R01 HL158801
6 · The paper itself

Abstract

Background Certain echocardiographic parameters may serve as early predictors of adverse events in patients with hemodynamically compromising pulmonary embolism (PE). Methods and Results An observational analysis was conducted for patients with acute pulmonary embolism evaluated by a Pulmonary Embolism Response Team (PERT) between 2014 and 2020. The performance of clinical prediction algorithms including the Pulmonary Embolism Severity Index and Carl Bova score were compared using a ratio of right ventricle and left ventricle hemodynamics by dividing the pulmonary artery systolic pressure by the left ventricle stroke volume. The primary outcome of in-hospital mortality, cardiac arrest, and the need for advanced therapies was evaluated by univariate and multivariable analyses. Of the 343 patients meeting the inclusion criteria, 215 had complete data. Pulmonary artery systolic pressure/left ventricle stroke volume was a clear predictor of the primary end point (odds ratio [OR], 2.31;

Indexed as

Pulmonary EmbolismVentricular Dysfunction, RightAcute DiseaseHeart VentriclesHumansPulmonary ArteryStroke Volumepulmonary artery pressurepulmonary embolismright ventriclestroke volume

Identifiers

PMID34482705
PMCPMC8649518

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.