Evidence map›Paper›PMID 34482623›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2022

Medical and nursing home costs: From cognitively unimpaired through dementia.

Kirsten Hall Long, Carin Smith, Ronald Petersen, Jane Emerson, Jeanine Ransom, Michelle M Mielke, Steven Hass, Cynthia Leibson

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Characterizing dementia among patients with spina bifida (SB).Translational andrology and urology · 2026
    Article
  2. Review
  3. Article
  4. Incremental Healthcare Costs of Dementia and Cognitive Impairment in Community-Dwelling Older Adults: A Prospective Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  5. Article
  6. Making a Case for Whole Person Health.Global advances in integrative medicine and health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kirsten Hall LongK Long Health Economics Consulting, LLC, St. Paul, Minnesota, USA.
Carin SmithDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Ronald PetersenDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Jane EmersonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Jeanine RansomDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Michelle M MielkeDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.
Steven HassDepartment of Health Economics and Outcomes Research, AbbVie, North Chicago, Illinois, USA.
Cynthia LeibsonDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, USA.

Funding

SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
Rochester Epidemiology ProjectR01AG034676 · NIA · MAYO CLINIC ROCHESTER · PI ROCCA, WALTER A, ST SAUVER, JENNIFER LYNN · 2010 to 2019
$9.5M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
NIA NIH HHS R01 AG034676NIA NIH HHS R33 AG058738NIA NIH HHS U01 AG006786
6 · The paper itself

Abstract

introductionEfforts to model the cost-effectiveness of managing/modifying cognitive impairment lack reliable, objective, baseline medical, and nursing-home (NH) costs.

methodsA stratified-random sample of Olmsted County, MN, residents ages 70-89 years (N = 3545), well-characterized as cognitively unimpaired, mild cognitive impairment (MCI), or dementia, were followed forward ≤1 year in provider-linked billing data and the Centers for Medicare & Medicaid Services NH assessments. Direct medical/nursing home/medical + NH costs were estimated. Costs were stratified by vital status and NH-use intensity (NH days/follow-up days [0%, 1% to 24%, 25% to 99%, and 100%]). Between-category mean-annual cost differences were adjusted for patient characteristics and follow-up days.

resultsCosts/follow-up day distributions differed significantly across cognitive categories. Mean costs/follow-up days were 2.5 to 18 times higher for decedents versus survivors. Among all persons with MCI, <9% with any NH use accounted for 18% of all total annual medical + NH costs. Adjusted-between-category comparisons revealed significantly higher medical and medical + NH costs for MCI versus cognitively unimpaired. DISCUSSION: Cost-effectiveness for managing/modifying both MCI and dementia should consider end-of-life costs and NH-use intensity. Results can help inform cost-effectiveness models, predict future-care needs, and aid decision-making by individuals/providers/payers/policymakers.

Indexed as

Cognitive DysfunctionDementiaAgedAged, 80 and overHumansMedicareMinnesotaNursing HomesUnited Statescognitive statuscostdementiaeconomicsmild cognitive impairmentnursing home

Identifiers

PMID34482623
PMCPMC8897513

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.