Evidence map›Paper›PMID 34482562›Full record

ArticleMedical physics2021

Tetrahedron beam imaging with a multi-pixel thermionic emission X-ray source and a photon-counting detector: A benchtop experimental study.

Qinghao Chen, Shuang Zhou, Yuewen Tan, Yao Hao, Zhongwei Zhang, Tom Mazur, Tiezhi Zhang

Open access · greenAbstract read
In one paragraph

Article in Medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qinghao ChenDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Shuang ZhouDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Yuewen TanDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Yao HaoDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Zhongwei ZhangDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Tom MazurDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Tiezhi ZhangDepartment of Radiation Oncology, Washington University in St. Louis, St. Louis, Missouri, USA.
Washington University in St. Louis · US

Funding

Novel Tetrahedron Beam CT for Point-of-Care Imaging in Ear, Nose, and ThroatR41EB026401 · NIBIB · TETRAIMAGING, LLC · PI WANG, LU, ZHANG, TIEZHI · 2018 to 2018
$225k
Super-resolution dual-energy dental CT based on distributed x-ray source and photon counting detectorR41DE029727 · NIDCR · TETRAIMAGING, LLC · PI TOKER, EMRE, ZHANG, TIEZHI · 2021 to 2021
$222k
DEVELOPMENT OF A NOVEL W-PG LAMINATE X-RAY TARGET WITH IMPROVED FOCAL SPOT POWER DENSITYR03EB024952 · NIBIB · WASHINGTON UNIVERSITY · PI ZHANG, TIEZHI · 2017 to 2018
$153k
NIBIB NIH HHS R03 EB024952NIBIB NIH HHS R41 EB026401NIDCR NIH HHS R41 DE029727
6 · The paper itself

Abstract

purposeA tetrahedron beam (TB) X-ray system with a linear X-ray source array and a linear detector array positioned orthogonal to each other may overcome the X-ray scattering problem of traditional cone-beam X-ray systems. We developed a TB imaging benchtop system using a linear array X-ray source to demonstrate the principle and benefits of TB imaging.

methodsA multi-pixel thermionic emission X-ray (MPTEX) source with 48 focal spots in 4-mm spacing was developed in-house. The X-ray beams are collimated to a stack of fan beams that are converged to a 6-mm wide multi-row photon-counting detector (PCD). The data collected with a sequential scan of the sources at a fixed view angle were synthesized to a 2D radiography image by a shift-and-add algorithm. The data collected with a full rotation of the system were reconstructed into 3D TB CT (TBCT) images using an Feldkamp, Davis, and Kress (FDK)-based computed tomography (CT) algorithm modified for the TB geometry.

resultsWith an 18.8-cm long source array and a 35-cm long detector array, the TB benchtop system provides a 25-cm cross-sectional and 8-cm axial field of view (FOV). The scatter-to-primary ratio (SPR) was approximately 17% for TB, as compared with 120% for cone beam geometry. The TBCT system enables reconstructions in two-dimensional radiography and three-dimensional volumetric CT. The TBCT images were free of "cupping" artifacts and have similar image quality as diagnostic helical CT.

conclusionsA TB imaging benchtop imaging system was successfully developed with MPTEX source and PCD. Phantom and animal cadaver imaging demonstrated that the TB system can produce satisfactory radiographic X-ray images and 3D CT images with image quality comparable to diagnostic helical CTs.

Indexed as

PhotonsTomography, X-Ray ComputedAlgorithmsCone-Beam Computed TomographyCross-Sectional StudiesPhantoms, ImagingX-Raysmulti-pixel thermionic emission X-ray sourcephoton-counting detectorscatter-to-primary ratiotetrahedron beam

Identifiers

PMID34482562
PMCPMC8595623
OpenAlexW3198034948

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.