Evidence map›Paper›PMID 34482505›Full record

ArticleBiological trace element research2022

Hydrogen-Rich Water Alleviates the Nickel-Induced Toxic Responses (Inflammatory Responses, Oxidative Stress, DNA Damage) and Ameliorates Cocoon Production in Earthworm.

Mine Köktürk, Serkan Yıldırım, Gizem Eser, Menekşe Bulut, Duried Alwazeer

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Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Article
  3. Research progress in clinical utilization of HFrontiers in pharmacology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mine KöktürkDepartment of Organic Agriculture Management, College of Applied Sciences, Igdir University, Igdir, Turkey.
Serkan YıldırımDepartment of Pathology, Faculty of Veterinary, Ataturk University, Erzurum, Turkey.
Gizem EserTuzluca Vocational School, Laboratory and Veterinary Health Programs, Igdir University, 76000 , Igdir, Turkey.
Menekşe BulutDepartment of Food Engineering, Faculty of Engineering, Igdir University, 76000, Igdir, Turkey.
Duried AlwazeerResearch Center for Redox Applications in Foods (RCRAF), Igdir University, 76000 , Igdir, Turkey. duried.alwazeer@igdir.edu.tr.ORCID http://orcid.org/0000-0002-2291-1628
Iğdır Üniversitesi · TRAtatürk University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, studies investigating the protective effect of hydrogen-rich water (HRW) against different diseases and the toxicity of some substances have attracted increasing attention. Here, we assessed the effects of hydrogen-rich water on different nickel-induced toxic responses (reactive oxygen species (ROS), tumor necrosis factor-alpha (TNF-α), and 8-hydroxy-2'-deoxyguanosine (8-OHdG) of stress responses, histopathological changes) and cocoon production in earthworm model. Earthworms were randomly divided into two main groups: water (W) group including control (CW: ultrapure water), 10 (10W), 200 (200W), and 500 (500W), and hydrogen-rich ultrapure water (HRW) group including control (CHRW: hydrogen-rich ultrapure water), 10 (10HRW), 200 (200HRW), and 500 (500HRW) mg of nickel chloride kg

Indexed as

HydrogenOligochaetaAnimalsDNA DamageEcosystemNecrosisNickelOxidative StressReactive Oxygen SpeciesSoilTumor Necrosis Factor-alphaWaterHydrogenNickelReactive Oxygen SpeciesSoilTumor Necrosis Factor-alphaWater8-OHdGCocoon productionEarthwormHydrogen-rich waterROSTNF-α

Identifiers

PMID34482505
OpenAlexW3196589757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.