ReviewTranslational psychiatry2021
Emerging imaging methods to study whole-brain function in rodent models.
Review in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Optogenetic fMRI for Brain-Wide Circuit Analysis of Sensory Processing.International journal of molecular sciences · 2022Pooled it
- Astrocyte-Driven Modulation of Whole-Brain Functional Networks and BOLD Signals Revealed by Optogenetic-fMRI.Neuroscience bulletin · 2026Article
- Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer's disease.Journal of biomedical optics · 2026Article
- The protocol for mesoscopic wide-field optical imaging in mice: from zero to hero.Biology methods & protocols · 2026Review
- Affordable miniaturized speckle contrast diffuse correlation tomography device for depth-sensitive mapping of cerebral blood flow in rodents.Journal of biomedical optics · 2025Article
- State-of-the-art preclinical techniques to study the impact of spreading depolarizations in awake rodents.The journal of headache and pain · 2025Review
- Western diet since adolescence impairs brain functional hyperemia at adulthood in mice: rescue by a balanced ω-3:ω-6 polyunsaturated fatty acids ratio.International journal of obesity (2005) · 2025Article
- Aging-dependent loss of functional connectivity in a mouse model of Alzheimer's disease and reversal by mGluR5 modulator.Molecular psychiatry · 2025Article
- Non-invasive Modulation of Deep Brain Nuclei by Temporal Interference Stimulation.Neuroscience bulletin · 2025Article
- Multimodal identification of the mouse brain using simultaneous CaCommunications biology · 2025Article
- Sex- and region-dependent neuroinflammation in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Somatosensory-evoked response induces extensive diffusivity and kurtosis changes associated with neural activity in rodents.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Effects of Environmental Noise Stress on Mouse Metabolism.International journal of molecular sciences · 2024Article
- Article
- Automatic monitoring of neural activity with single-cell resolution in behaving Hydra.Scientific reports · 2024Article
- Fantastic beasts and how to study them: rethinking experimental animal behavior.The Journal of experimental biology · 2024Article
- Low-cost reversible tandem lens mesoscope for brain imaging in rodents.Neurophotonics · 2024Article
- Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Automatic monitoring of whole-body neural activity in behavingbioRxiv : the preprint server for biology · 2023Article
- Evaluation of cellular activity in response to sleep deprivation by a comprehensive analysis of the whole mouse brain.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past decade, the idea that single populations of neurons support cognition and behavior has gradually given way to the realization that connectivity matters and that complex behavior results from interactions between remote yet anatomically connected areas that form specialized networks. In parallel, innovation in brain imaging techniques has led to the availability of a broad set of imaging tools to characterize the functional organization of complex networks. However, each of these tools poses significant technical challenges and faces limitations, which require careful consideration of their underlying anatomical, physiological, and physical specificity. In this review, we focus on emerging methods for measuring spontaneous or evoked activity in the brain. We discuss methods that can measure large-scale brain activity (directly or indirectly) with a relatively high temporal resolution, from milliseconds to seconds. We further focus on methods designed for studying the mammalian brain in preclinical models, specifically in mice and rats. This field has seen a great deal of innovation in recent years, facilitated by concomitant innovation in gene-editing techniques and the possibility of more invasive recordings. This review aims to give an overview of currently available preclinical imaging methods and an outlook on future developments. This information is suitable for educational purposes and for assisting scientists in choosing the appropriate method for their own research question.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.