Evidence map›Paper›PMID 34482301›Full record

ArticleActa crystallographica. Section C, Structural chemistry2021

Mechanochemical synthesis insights and solid-state characterization of quininium aspirinate, a glass-forming drug-drug salt.

Nehemiah Harris, Jubilee Benedict, Diane A Dickie, Silvina Pagola

Abstract read
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In one paragraph

Article in Acta crystallographica. Section C, Structural chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nehemiah HarrisDepartment of Chemistry and Biochemistry, Old Dominion University, 4402 Elkhorn Ave., Norfolk, VA 23529, USA.
Jubilee BenedictDepartment of Chemistry and Biochemistry, Old Dominion University, 4402 Elkhorn Ave., Norfolk, VA 23529, USA.
Diane A DickieDepartment of Chemistry, University of Virginia, Charlottesville, VA 22904, USA.
Silvina PagolaDepartment of Chemistry and Biochemistry, Old Dominion University, 4402 Elkhorn Ave., Norfolk, VA 23529, USA.ORCID 0000-0003-2083-7599

Funding

MARC Undergraduate Student Training in Academic Research Program at Old Dominion UniversityT34GM118259 · NIGMS · OLD DOMINION UNIVERSITY · PI HOLDER, ALVIN ANDERSON · 2018 to 2022
$1.6M
International Centre for Diffraction Data GIA 08-04National Institutes of Health, National Institute of General Medical Sciences T34GM118259NIGMS NIH HHS T34 GM118259
6 · The paper itself

Abstract

Quinine (an antimalarial) and aspirin (a nonsteroidal anti-inflammatory drug) were combined into a new drug-drug salt, quininium aspirinate, C

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAspirinCalorimetry, Differential ScanningCrystallography, X-RayHydrogen BondingPharmaceutical PreparationsPhase TransitionQuinineSolubilitySpectroscopy, Fourier Transform InfraredThermogravimetryX-Ray DiffractionAnti-Inflammatory Agents, Non-SteroidalAspirinPharmaceutical PreparationsQuinineantimalarialaspirincrystal structuredrug–drug saltliquid-assisted grindingmechanochemistryNSAIDquinine

Identifiers

PMID34482301
PMCPMC8418670

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.