Evidence map›Paper›PMID 34482293›Full record

ArticleActa crystallographica. Section C, Structural chemistry2021

Anthelmintic flavonoids and other compounds from Combretum glutinosum Perr. ex DC (Combretaceae) leaves.

Placide M Toklo, Eléonore Yayi Ladekan, Anthony Linden, Sylvie Hounzangbe-Adote, Siméon F Kouam, Joachim D Gbenou

Open access · hybridAbstract read
In one paragraph

Article in Acta crystallographica. Section C, Structural chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. A Narrative Review of the Biological Activities ofJournal of experimental pharmacology · 2025
    Review
  3. Anthelminthic Activity ofScientifica · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Placide M TokloLaboratoire de Pharmacognosie et des Huiles Essentielles, Facultés des Sciences et Techniques, Université d'Abomey Calavi, 01 BP: 918 ISBA Cotonou, Benin.
Eléonore Yayi LadekanLaboratoire de Pharmacognosie et des Huiles Essentielles, Facultés des Sciences et Techniques, Université d'Abomey Calavi, 01 BP: 918 ISBA Cotonou, Benin.
Anthony LindenDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.ORCID 0000-0002-9343-9180
Sylvie Hounzangbe-AdoteLaboratoire d'Ethnopharmacologie et de Santé Animale, Faculté des Sciences Agronomiques, Université d'Abomey Calavi, 01 BP: 526 Cotonou, Benin.
Siméon F KouamDepartment of Chemistry, Higher Teacher Training College, University of Yaounde I, PO Box 47, 4124 Yaounde, Cameroon.
Joachim D GbenouLaboratoire de Pharmacognosie et des Huiles Essentielles, Facultés des Sciences et Techniques, Université d'Abomey Calavi, 01 BP: 918 ISBA Cotonou, Benin.
University of Notre Dame · USUniversité d'Abomey-Calavi · BJUniversité de Yaoundé I · CMUniversity of Zurich · CH

Funding

DAAD 57316173Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 206021_164018
6 · The paper itself

Abstract

A chemical study of the hydro-ethanol extract of the leaves of Combretum glutinosum resulted in the isolation of nine compounds, including 5-demethylsinensetin (1), umuhengerin (2), (20S,24R)-ocotillone (3), lupeol (4), β-sitosterol (5), oleanolic acid (6), betulinic acid (7), corymbosin (8) and β-sitosterol glucoside (9). Four compounds have been isolated for the first time from the genus Combretum [viz. (1), (2), (3) and (8)]. The crystal structures of flavonoid (2), C

Indexed as

AnimalsAnthelminticsAnti-Infective AgentsCombretaceaeCombretumCrystallography, X-RayFlavonesFlavonoidsHaemonchusHydrogen BondingLarvaPlant LeavesAnthelminticsAnti-Infective AgentsFlavonesFlavonoidsumuhengerinabsolute configurationanthelminticC. glutinosumcrystal structureflavonoidsnatural producttriterpenes

Identifiers

PMID34482293
PMCPMC8418671
OpenAlexW3191199326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.