Evidence map›Paper›PMID 34482264›Full record

ArticleThe International journal on drug policy2021

Targeting community-based naloxone distribution using opioid overdose death rates: A descriptive analysis of naloxone rescue kits and opioid overdose deaths in Massachusetts and Rhode Island.

Xiao Zang, Alexandria Macmadu, Maxwell S Krieger, Czarina N Behrends, Traci C Green, Jake R Morgan, Sean M Murphy, Shayla Nolen, Alexander Y Walley, Bruce R Schackman and 1 more

Abstract read
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Article in The International journal on drug policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

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0cells of the map it votes in
23citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Xiao ZangDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States.
Alexandria MacmaduDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States.
Maxwell S KriegerDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States.
Czarina N BehrendsDepartment of Healthcare Policy and Research, Weill Cornell Medical College, New York City, New York, United States.
Traci C GreenInstitute for Behavioral Health, School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, United States.
Jake R MorganDepartment of Health Law, Policy, and Management, Boston University School of Public Health, Boston, Massachusetts, United States.
Sean M MurphyDepartment of Healthcare Policy and Research, Weill Cornell Medical College, New York City, New York, United States.
Shayla NolenDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States.
Alexander Y WalleyDepartment of Medicine, Section of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, United States.
Bruce R SchackmanDepartment of Healthcare Policy and Research, Weill Cornell Medical College, New York City, New York, United States.
Brandon Dl MarshallDepartment of Epidemiology, School of Public Health, Brown University, Providence, Rhode Island, United States. Electronic address: brandon_marshall@brown.edu.

Funding

Utilization of health services after engagement with opioid use disorder (OUD) treatment provider by individuals with and without post-traumatic stress disorderP30DA040500 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ZACHARY Franklin MEISEL · 2015 to 2026
$20.7M
DAT-18-06 Prevention and Rescue Of Fentanyl and Other Opioid Overdoses Using Optimized Naloxone Distribution Strategies (PROFOUND)U01DA047408 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARSHALL, BRANDON DAVID LEWIS, SCHACKMAN, BRUCE R · 2019 to 2023
$3.5M
NIDA NIH HHS P30 DA040500NIDA NIH HHS U01 DA047408
6 · The paper itself

Abstract

backgroundRates of fatal opioid overdose in Massachusetts (MA) and Rhode Island (RI) far exceed the national average. Community-based opioid education and naloxone distribution (OEND) programs are effective public health interventions to prevent overdose deaths. We compared naloxone distribution and opioid overdose death rates in MA and RI to identify priority communities for expanded OEND.

methodsWe compared spatial patterns of opioid overdose fatalities and naloxone distribution through OEND programs in MA and RI during 2016 to 2019 using public health department data. The county-level ratio of naloxone kits distributed through OEND programs per opioid overdose death was estimated and mapped to identify potential gaps in naloxone availability across geographic regions and over time.

resultsFrom 2016 to 2019, the statewide community-based naloxone distribution to opioid overdose death ratio improved in both states, although more rapidly in RI (from 11.8 in 2016 to 35.6 in 2019) than in MA (from 12.3 to 17.2), driven primarily by elevated and increasing rates of naloxone distribution in RI. We identified some urban/non-urban differences, with higher naloxone distribution relative to opioid overdose deaths in more urban counties, and we observed some counties with high rates of overdose deaths but low rates of naloxone kits distributed through OEND programs.

conclusionsWe identified variations in spatial patterns of opioid overdose fatalities and naloxone availability, and these disparities appeared to be widening in some areas over time. Data on the spatial distribution of naloxone distribution and opioid overdose deaths can inform targeted, community-based naloxone distribution strategies that optimize resources to prevent opioid overdose fatalities.

Indexed as

Drug OverdoseOpiate OverdoseOpioid-Related DisordersAnalgesics, OpioidHumansMassachusettsNaloxoneNarcotic AntagonistsRhode IslandAnalgesics, OpioidNaloxoneNarcotic AntagonistsCommunity-based opioid education and naloxone distributionDescriptive analysisOpioid overdose deathSpatial patterns

Identifiers

PMID34482264
PMCPMC8671216

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.