ArticleJournal of the American Academy of Child and Adolescent Psychiatry2022
Preschool Irritability Predicts Adolescent Psychopathology and Functional Impairment: A 12-Year Prospective Study.
Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Understanding irritability through the lens of self-regulatory control processes in children and adolescents: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- Prevalence, comorbidity, and demographic patterns of oppositional defiant disorder and conduct disorder in Chinese children and adolescents: a systematic review.Frontiers in psychology · 2025Pooled it
- Systematic Review and Meta-Analysis: Early Irritability as a Transdiagnostic Neurodevelopmental Vulnerability to Later Mental Health Problems.Journal of the American Academy of Child and Adolescent Psychiatry · 2024Pooled it
- Examining Associations Between the Timing of Maternal Depressive Symptoms, Parenting Behaviors, and Child Outcomes.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Discrete components of stress impact trajectories of childhood irritability but not adolescent mental health outcomes.JCPP advances · 2026Article
- Ultra-processed food consumption during pregnancy and emotional and behavioral problems in offspring.European child & adolescent psychiatry · 2026Article
- Article
- Irritability in preschool children with attention-deficit/hyperactivity disorder: Analysis of family environmental factors.JCPP advances · 2026Article
- Youth Irritability as Consequence and Predictor of Family Conflict From Late Childhood to Early Adolescence.Child psychiatry and human development · 2026Article
- Comparison of Global and Daily Ratings of Associations between Anxiety and Depressive Behaviors and Impairment in Preschool-Aged Children.Child psychiatry and human development · 2026Article
- Inhibition-related connectivity predicts irritability risk and resilience across early adolescence.Social cognitive and affective neuroscience · 2026Article
- Understanding the Etiology of Externalizing Problems in Young Children: The Roles of Callous-Unemotional Traits and Irritability.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Article
- Article
- Rumination Mediates the Relation of Hostile Attribution to Psychological Maladjustment Among Adolescents from Three Countries.Research on child and adolescent psychopathology · 2025Article
- The hidden burden: self-reported irritability in adolescent girls signals higher psychiatric risk.BMC public health · 2025Article
- Genetic and Environmental Influences on the Development of Irritability from Ages 3 to 5 Years.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2025Article
- Irritability: associations with real-time affect dynamics, social interactions, and daily substance use in older adolescents.European child & adolescent psychiatry · 2025Article
- Assessing Whether Negative Parenting Cognitions Bias Parent Report of Preschoolers' Externalizing Symptoms: A Regularized Moderated Non-Linear Factor Analysis Approach.Research on child and adolescent psychopathology · 2025Article
- Preschool Behavioral Problems: Links with Maternal Oxytocin and Caregiving Sensitivity in the Postnatal Period, and Concurrent Maternal Psychopathology and Attachment State-of-Mind.Child psychiatry and human development · 2024Article
- Neural mechanisms of inhibitory control in preadolescent irritability: Insights from the ABCD study.Biological psychology · 2024Article
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6 authors at 4 institutions in 1 country.
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Abstract
objectiveThe long-term clinical and functional outcomes of preschool-age irritability are unknown. This study examined longitudinal associations of preschool irritability with psychiatric disorders and functional impairment assessed in adolescence in a large community sample.
methodA total of 453 children were assessed at age 3 and again at ages 12 and/or 15. At age 3, parents were interviewed about their child's irritability, other psychiatric symptoms, and functional impairment with the Preschool Age Psychiatric Assessment (PAPA). In adolescence, both parents and youths were interviewed with the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime (K-SADS-PL) to assess youth psychopathology and functional impairment; youths also completed the UCLA Life Stress Interview (LSI) to assess different domains of functioning. Lastly, youths and parents completed the Children's Depression Inventory 2 (CDI 2) and the Screen for Child Anxiety Related Disorders (SCARED).
resultsIrritability at age 3 predicted internalizing and externalizing disorders in adolescence; parent-reported anxiety and depressive symptoms; and greater functional impairment, including poorer peer functioning, poorer physical health, and antidepressant and educational service use, even after controlling for baseline psychiatric disorders. All longitudinal associations persisted after further adjusting for well-established early life risk markers for psychopathology.
conclusionThe findings of this study underscore the clinical significance and predictive power of preschool irritability and provide support for its use in large-scale identification and intervention efforts.
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