Evidence map›Paper›PMID 34481480›Full record

ArticleBMC musculoskeletal disorders2021

Vertebral fracture as a risk factor for self-harm: a retrospective cohort study.

James A Prior, Fay Crawford-Manning, Rebecca Whittle, Alyshah Abdul-Sultan, Carolyn A Chew-Graham, Sara Muller, Tom A Shepherd, Athula Sumathipala, Christian D Mallen, Zoe Paskins

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

James A PriorPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK. j.a.prior@keele.ac.uk.
Fay Crawford-ManningPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Rebecca WhittlePrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Alyshah Abdul-SultanPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Carolyn A Chew-GrahamPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Sara MullerPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Tom A ShepherdPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Athula SumathipalaPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Christian D MallenPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Zoe PaskinsPrimary Care Centre Versus Arthritis, School of Medicine, Keele University, ST5 5BG, Staffordshire, UK.
Versus Arthritis · GBKeele University · GB

Funding

Collaboration for Leadership in Applied Health Research and Care - Greater Manchester (GB) CS-2018-18-ST2-010National institute for health research 349National Institute for Health Research National Institute for Health ResearchNational Institute for Health Research NIHR-RP-2014-04-026
6 · The paper itself

Abstract

backgroundThe prevention of self-harm is an international public health priority. It is vital to identify at-risk populations, particularly as self-harm is a risk factor for suicide. This study aims to examine the risk of self-harm in people with vertebral fractures.

methodsRetrospective cohort study. Patients with vertebral fracture were identified within the Clinical Practice Research Datalink and matched to patients without fracture by sex and age. Incident self-harm was defined by primary care record codes following vertebral fracture. Overall incidence rates (per 10,000 person-years (PY)) were reported. Cox regression analysis determined risk (hazard ratios (HR), 95 % confidence interval (CI)) of self-harm compared to the matched unexposed cohort. Initial crude analysis was subsequently adjusted and stratified by median age and sex.

resultsThe number of cases of vertebral fracture was 16,293, with a matched unexposed cohort of the same size. Patients were predominantly female (70.1 %), median age was 76.3 years. Overall incidence of self-harm in the cohort with vertebral fracture was 12.2 (10.1, 14.8) /10,000 PY. There was an initial crude association between vertebral fracture and self-harm, which remained after adjustment (HR 2.4 (95 %CI 1.5, 3.6). Greatest risk of self-harm was found in those with vertebral fractures who were aged below 76.3 years (3.2(1.8, 5.7)) and male (3.9(1.8, 8.5)).

conclusionsPrimary care patients with vertebral fracture are at increased risk of self-harm compared to people without these fractures. Male patients aged below 76 years of age appear to be at greatest risk of self-harm. Clinicians need to be aware of the potential for self-harm in this patient group.

Indexed as

Self-Injurious BehaviorSpinal FracturesAgedCohort StudiesFemaleHumansIncidenceMaleRetrospective StudiesRisk FactorsPrimary careSelf-harmVertebral fracture

Identifiers

PMID34481480
PMCPMC8417993
OpenAlexW3111527045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.