ArticleLasers in surgery and medicine2022
A pilot feasibility study to assess vascularity and perfusion of parathyroid glands using a portable hand-held imager.
Article in Lasers in surgery and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Review
- The research progress of label-free optical imaging technology in intraoperative real-time navigation of parathyroid glands.Lasers in medical science · 2025Review
- Methods for the identification and preservation of parathyroid glands in thyroid surgery: a narrative review.Gland surgery · 2023Review
- Unsupervised and quantitative intestinal ischemia detection using conditional adversarial network in multimodal optical imaging.Journal of medical imaging (Bellingham, Wash.) · 2022Article
- A coaxial excitation, dual-red-green-blue/near-infrared paired imaging system toward computer-aided detection of parathyroid glands in situ and ex vivo.Journal of biophotonics · 2022Article
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
objectivesIntraoperative localization and preservation of parathyroid glands (PGs) are challenging during thyroid surgery. A new noninvasive technique of combined near-infrared PG autofluorescence detection and dye-free imaging angiography that allows intraoperative feedback has recently been introduced. The objective of this study was to evaluate this technique in real-time. MATERIALS AND
methodsA pilot feasibility study of a portable imaging device in four patients who underwent either thyroid lobectomy or total thyroidectomy is presented. PG autofluorescence and vascularity/tissue perfusion were monitored using a real-time screen display during the surgical procedure.
resultsThree lobectomies and one total thyroidectomy were performed. Among the nine PGs identified by the operating surgeon, eight PGs were confirmed using the autofluorescence device. Each PG was successfully determined to be either well-perfused or devascularized, and devascularized PGs were autotransplanted.
conclusionsThe preliminary results suggest that the combination of PG autofluorescence detection and dye-free angiography can potentially be used to assess PG function. With further validation studies, the effectiveness of this technique in clinical practice can be further delineated.
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