Evidence map›Paper›PMID 34481097›Full record

ArticleBrain stimulation

Two forms of short-interval intracortical inhibition in human motor cortex.

Po-Yu Fong, Danny Spampinato, Lorenzo Rocchi, Ricci Hannah, Yinghui Teng, Alessandro Di Santo, Mohamed Shoura, Kailash Bhatia, John C Rothwell

Abstract read
In one paragraph

Article in Brain stimulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
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  8. Amelioration of Focal Hand Dystonia via Low-Frequency Repetitive Somatosensory Stimulation.Movement disorders : official journal of the Movement Disorder Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Po-Yu FongDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK; Division of Movement Disorders, Department of Neurology and Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan; Medical School, College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address: po-yu.fong.18@ucl.ac.uk.
Danny SpampinatoDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK; Non-invasive Brain Stimulation Unit, IRCCS Santa Lucia Foundation, Via Ardeatina 306/354, 00142, Rome, Italy.
Lorenzo RocchiDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK; Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Ricci HannahDepartment of Psychology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Yinghui TengDivision of Biosciences, University College London, London, UK.
Alessandro Di SantoDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK; Neurology, Neurophysiology and Neurobiology Unit, Department of Medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Mohamed ShouraDepartment of Neurology, Heliopolis and Al Azhar University Hospitals, Cairo, Egypt.
Kailash BhatiaDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK.
John C RothwellDepartment of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK.

Funding

Medical Research Council MR/P006671/1
6 · The paper itself

Abstract

backgroundPulses of transcranial magnetic stimulation (TMS) with a predominantly anterior-posterior (AP) or posterior-anterior (PA) current direction over the primary motor cortex appear to activate distinct excitatory inputs to corticospinal neurons. In contrast, very few reports have examined whether the inhibitory neurons responsible for short-interval intracortical inhibition (SICI) are sensitive to TMS current direction.

objectivesTo investigate whether SICI evaluated with AP and PA conditioning stimuli (CS

methodsUsing two superimposed TMS coils, CS

resultsCS

conclusionsSICI

Indexed as

Motor CortexElectromyographyEvoked Potentials, MotorHumansNeural InhibitionTranscranial Magnetic StimulationCoil orientationInhibitory circuitMovement preparationSICITMSTriple pulse stimulation

Identifiers

PMID34481097
PMCPMC8460995

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.