Evidence map›Paper›PMID 34481070›Full record

ArticleContemporary clinical trials2021

Effectiveness of a smoking cessation algorithm integrated into HIV primary care: Study protocol for a randomized controlled trial.

Samantha M McKetchnie, Conall O'Cleirigh, Heidi M Crane, Samantha V Hill, David Prior, Matteo Peretti, Mariel Parman, Douglas E Levy, Dustin Long, Karen Cropsey

Open access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Interventions for tobacco use cessation in people living with HIV.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Tobacco Use and Treatment of Tobacco Dependence Among People With Human Immunodeficiency Virus: A Practical Guide for Clinicians.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Samantha M McKetchnieThe Fenway Institute, Fenway Community Health, Boston, MA, United States of America; Behavioral Medicine Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America; School of Social Work, Boston College, Newton, MA, United States of America. Electronic address: Smarquez1@mgh.harvard.edu.
Conall O'CleirighThe Fenway Institute, Fenway Community Health, Boston, MA, United States of America; Behavioral Medicine Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America; Harvard Medical School, Harvard University, Boston, MA, United States of America.
Heidi M CraneDepartment of Medicine, University of Washington, Seattle, WA, United States of America.
Samantha V HillDepartment of Pediatrics, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States of America.
David PriorThe Fenway Institute, Fenway Community Health, Boston, MA, United States of America.
Matteo PerettiThe Fenway Institute, Fenway Community Health, Boston, MA, United States of America.
Mariel ParmanDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Douglas E LevyHarvard Medical School, Harvard University, Boston, MA, United States of America; Health Policy Research Center, Mongan Institute, Massachusetts General Hospital, Boston, MA, United States of America.
Dustin LongDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Karen CropseyDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
University of Alabama at Birmingham · USUniversity of Washington · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Effectiveness of a smoking cessation algorithm integrated into HIV primary careR01DA044112 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CRANE, HEIDI M., CROPSEY, KAREN L · 2018 to 2022
$3.5M
Patient-Oriented Substance Use/Smoking Cessation Research in HIV Treatment and PreventionK24DA062568 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Conall Michael O'Cleirigh · 2024 to 2026
$639k
NIAID NIH HHS P30 AI027757NIDA NIH HHS K24 DA062568NIDA NIH HHS R01 DA044112
6 · The paper itself

Abstract

backgroundWhile addressing smoking cessation in the context of HIV primary care may increase the acceptability of smoking cessation treatment for patients, HIV care providers have not been trained in offering these treatments. Tools that aid providers in treatment selection, such as computer-generated algorithms, may address barriers to providing effective and efficient treatment options to their patients.

objectiveTo test the effectiveness of a computer-generated smoking cessation pharmacotherapy recommendation algorithm fully integrated into HIV primary care against an enhanced usual care condition.

methodsSix hundred adult smokers living with HIV will be recruited from 3 medical clinics that provide HIV care in Birmingham, AL, Seattle, WA, and Boston, MA. Participants will be asked to complete a baseline visit and 4 follow-up visits, which will include self-report assessments and carbon monoxide monitoring. Additionally, participants have the option to respond to weekly text-message based surveys sent over an 11-week period between baseline and end of treatment. Participants randomized to the AT condition will have a tailored, algorithm-generated smoking cessation pharmacotherapy recommendation delivered to their HIV care provider via EHR, with the potential to receive up to 12 weeks of smoking cessation pharmacotherapy.

conclusionsA smoking cessation pharmacotherapy recommendation algorithm integrated into HIV primary care may increase treatment utilization and smoking abstinence among smokers living with HIV. If successful, the intervention would be ready for use across the entire CFAR Network of Integrated Clinical Systems network and, more broadly, in HIV clinics that utilize an EHR system.

Indexed as

HIV InfectionsSmoking CessationAdultAlgorithmsHumansPrimary Health CareRandomized Controlled Trials as TopicTobacco Use Cessation DevicesAlgorithmHIVSmoking cessationTobacco use

Identifiers

PMID34481070
PMCPMC8607828
OpenAlexW3198384505

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.