Evidence map›Paper›PMID 34480841›Full record

ArticleJournal of applied clinical medical physics2021

Nontoxic electron collimators.

Dylan Yamabe Breitkreutz, Lawrie Skinner, Stephanie Lo, Amy Yu

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Article
  5. Transitioning to Environmentally Sustainable, Climate-Smart Radiation Oncology Care.International journal of radiation oncology, biology, physics · 2022
    Article
  6. Nontoxic electron collimators.Journal of applied clinical medical physics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dylan Yamabe BreitkreutzDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0002-0180-6538
Lawrie SkinnerDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0001-7317-1642
Stephanie LoDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.
Amy YuDepartment of Radiation Oncology, Stanford University, Stanford, California, USA.ORCID https://orcid.org/0000-0002-9730-5593
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe goal of this work was to develop and test nontoxic electron collimation technologies for clinical use.

methodsTwo novel technologies were investigated: tungsten-silicone composite and 3D printed electron cutouts. Transmission, dose uniformity, and profiles were measured for the tungsten-silicone. Surface dose, relative dose output, and field size were measured for the 3D printed cutouts and compared with the standard cerrobend cutouts in current clinical use. Quality assurance tests including mass measurements, Megavoltage (MV) imaging, and drop testing were developed for the 3D printed cutouts as a guide to safe clinical implementation.

resultsDose profiles of the flexible tungsten-silicone skin shields had an 80-20 penumbra values of 2-3 mm compared to 7-8 mm for cerrobend. In MV transmission image measurements of the tungsten-silicone, 80% of the pixels had a transmission value within 2% of the mean. An ∼90% reduction in electron intensity was measured for 6 MeV and a 6.4 mm thickness of tungsten-silicone and 12.7 mm thickness for 16 MeV. The maximum difference in 3D printed cutout versus cerrobend output, surface dose, and full width at half-maximum (FWHM) was 1.7%, 1.2%, and 1.5%, respectively, for the 10 cm × 10 cm cutouts.

conclusionsBoth flexible tungsten-silicone and 3D printed cutouts were found to be feasible for clinical use. The flexible tungsten-silicone was of adequate density, flexibility, and uniformity to serve as skin shields for electron therapy. The 3D printed cutouts were dosimetrically equivalent to standard cerrobend cutouts and were robust enough for handling in the clinical environment.

Indexed as

ElectronsRadiotherapy Planning, Computer-AssistedHumansRadionuclide ImagingTungstenTungsten3D printingelectron therapyskin collimation

Identifiers

PMID34480841
PMCPMC8504586
OpenAlexW3197725297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.