ArticleJournal of applied clinical medical physics2021
Image-guided volumetric-modulated arc therapy of total body irradiation: An efficient workflow from simulation to delivery.
Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The trial behind it
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Incorporating Intensity Modulated Total Body Irradiation (IMRT-TBI) Into Future Cooperative Group Clinical Trials: An NRG Hematologic Malignancies Working Group-Led Report From the National Clinical Trials Network.International journal of radiation oncology, biology, physics · 2026Article
- In vivo dosimetry using an electronic portal imaging device for pediatric myeloablative Total body irradiation with volumetric modulated arc therapy.Physics and imaging in radiation oncology · 2026Article
- Myeloablative Total Body Irradiation With Volumetric Modulated Arc Therapy for Children-a Single Center Experience.Advances in radiation oncology · 2026Article
- Dosimetric impact of port number in TomoDirect-based lower-body total body irradiation.Journal of applied clinical medical physics · 2026Article
- A comparative dosimetric evaluation of two image-guided calibration strategies for multi-isocenter total body irradiation: integrated fan-beam CT-based alignment versus sequential cone-beam CT-guided localization.Frontiers in oncology · 2026Article
- The Spinning Manny Indexed Overlay System for VMAT total body irradiation.Journal of applied clinical medical physics · 2026Article
- Feasibility of segmental total body irradiation (SegTBI) using a 1.5T MR-linac.Journal of applied clinical medical physics · 2025Article
- A multi-institutional survey on technical variations in total body irradiation in Japan.Radiological physics and technology · 2025Article
- The implementation of low instantaneous dose rate total body irradiation with linear accelerator in small-size treatment rooms.Journal of applied clinical medical physics · 2024Article
- Treatment robustness of total body irradiation with volumetric modulated arc therapy.Physics and imaging in radiation oncology · 2024Article
- Considerations for intensity modulated total body or total marrow and lymphoid irradiation.Clinical and translational radiation oncology · 2023Article
- Automatic planning of the lower extremities for total marrow irradiation using volumetric modulated arc therapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023Article
- Optimised conformal total body irradiation: a heterogeneous practice, so where next?The British journal of radiology · 2023Review
- Three-dimensional printers applied for the production of beam blocks in total body irradiation treatment.Journal of applied clinical medical physics · 2022Article
- Image-guided volumetric-modulated arc therapy of total body irradiation: An efficient workflow from simulation to delivery.Journal of applied clinical medical physics · 2021Article
- Dosimetric Performance Analysis of Pediatric Based Halcyon™ Volumetric Arc Therapy-Based Lung-Sparing Total Body Irradiation.Technology in cancer research & treatmentArticle
- Bridging Precision and Practice: A Systematic Approach to Total Body Irradiation in Routine Clinical Settings.Journal of medical physicsArticle
- Feasibility and Toxicity of Full-Body Volumetric Modulated Arc Therapy Technique for High-Dose Total Body Irradiation.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionUsing multi-isocenter volumetric-modulated arc therapy (VMAT) for total body irradiation (TBI) may improve dose uniformity and vulnerable tissue protection compared with classical whole-body field technique. Two drawbacks limit its application: (1) VMAT-TBI planning is time consuming; (2) VMAT-TBI plans are sensitive to patient positioning uncertainties due to beam matching. This study presents a robust planning technique with image-guided delivery to improve dose delivery accuracy. In addition, a streamlined sim-to-treat workflow with automatic scripts is proposed to reduce planning time. MATERIALS: Twenty-five patients were included in this study. Patients were scanned in supine head-first and feet-first directions. An automatic workflow was used to (1) create a whole-body CT by registering two CT scans, (2) contour lungs, kidneys, and planning target volume (PTV), (3) divide PTV into multiple sub-targets for planning, and (4) place isocenters. Treatment planning included feathered AP/PA beams for legs/feet and VMAT for the body. VMAT-TBI was evaluated for plan quality, planning/delivery time, and setup accuracy using image guidance.
resultsVMAT-TBI planning time can be reduced to a day with automatic scripts. Treatment time took around an hour per fraction. VMAT-TBI improved dose coverage (PTV V100 increased from 76.8 ± 10.5 to 88.5 ± 2.6; p < 0.001) and reduced lung dose (lung mean dose reduced from 10.8 ± 0.7 Gy to 9.4 ± 0.8 Gy, p < 0.001) compared with classic AP/PA technique.
conclusionA VMAT-TBI sim-to-treat workflow with robust planning and image-guided delivery was proposed. VMAT-TBI improved the plan quality compared with classical whole-body field techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.