ArticleJournal of applied microbiology2022
Hypochlorous acid solution is a potent antiviral agent against SARS-CoV-2.
Article in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Comparison of hyaluronic acid, hypochlorous acid, and flurbiprofen on postoperative morbidity in palatal donor area: a randomized controlled clinical trial.Clinical oral investigations · 2023Trial
- Trial
- Morphology-Evolving Colorimetric Thin-Film Sensor for Visual Detection of Hypochlorous Acid.Sensors (Basel, Switzerland) · 2026Article
- Hypochlorous Acid: Clinical Insights and Experience in Dermatology, Surgery, Dentistry, Ophthalmology, Rhinology, and Other Specialties.Biomedicines · 2025Review
- Commercially available antiseptics show highFrontiers in veterinary science · 2025Article
- Evaluation of the efficacy of chlorous acid water and sodium hypochlorite solution against SARS-CoV-2 in the presence of organic matter.Access microbiology · 2025Article
- Electrochemical HOCl Production Modeling for an Electrochemical Catheter.Journal of the Electrochemical Society · 2024Article
- Article
- Virucidal efficacy of hypochlorous acid water for aqueous phase and atomization against SARS-CoV-2.Journal of water and health · 2024Article
- The HOCl dry fog-is it safe for human cells?PloS one · 2024Article
- Antiviral Natural Products, Their Mechanisms of Action and Potential Applications as Sanitizers and Disinfectants.Food and environmental virology · 2023Review
- The Bacteriophages Therapy of Interdigital Pyoderma Complicated by Cellulitis with Antibiotic-ResistantVeterinary sciences · 2023Article
- Hypochlorous Acid as a Potential Postsurgical Antimicrobial Agent in Periodontitis: A Randomized, Controlled, Non-Inferiority Trial.Antibiotics (Basel, Switzerland) · 2023Article
- 0.01% Hypochlorous Acid Treats Aspergillus fumigatus Keratitis in Rats by Reducing Fungal Load and Inhibiting the Inflammatory Response.Translational vision science & technology · 2023Article
- Surface Inactivation of a SARS-CoV-2 Surrogate with Hypochlorous Acid is Impacted by Surface Type, Contact Time, Inoculum Matrix, and Concentration.Food and environmental virology · 2023Article
- Water bath is more efficient than hot air oven at thermal inactivation of coronavirus.Virology journal · 2023Article
- Isolation, molecular characterization, and disinfectants susceptibility of swine-carried mammalian orthoreoviruses in Japan in 2020-2022.The Journal of veterinary medical science · 2023Article
- Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections.GMS hygiene and infection control · 2023Review
- Virus purification highlights the high susceptibility of SARS-CoV-2 to a chlorine-based disinfectant, chlorous acid.PloS one · 2023Article
- Calcium bicarbonate as an antimicrobial, antiviral, and prion-inhibiting agent (Review).Biomedical reports · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
aimA novel coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suddenly appeared in Wuhan, China, and has caused pandemic. In this study, we evaluated antiviral activity of purified hypochlorous acid (HClO) against coronaviruses such as SARS-CoV-2 and transmissible gastroenteritis virus (TGEV) responsible for pig diseases. MATERIALS AND
resultsIn a suspension test, 28.1 ppm HClO solution inactivated SARS-CoV-2 in phosphate-buffered saline with the reduction of 10
conclusionsIn a carrier test, 125 ppm HClO solution for 10 min incubation is adequate to inactivate 4 logs TCID SIGNIFICANCE AND IMPACT OF THE STUDY: Effectiveness of HClO solution against SARS-CoV-2 was demonstrated by both suspension and carrier tests. HClO solution inactivated SARS-CoV-2 by 5 logs TCID
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.