Evidence map›Paper›PMID 34480818›Full record

ReviewHead & neck2021

Intraoral radiation stents-Primer for clinical use in head and neck cancer therapy.

Annu Singh, Evan B Rosen, Joseph D Randazzo, Cherry L Estilo, Daphna Y Gelblum, Joseph M Huryn

Abstract readReview
In one paragraph

Review in Head & neck, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Cancer therapy-related salivary dysfunction.The Journal of clinical investigation · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Protective and positioning devices in maxillofacial prosthodontics and radiotherapy: Overview.Technical innovations & patient support in radiation oncology · 2022
    Review
  13. Dental Evaluation Prior to Cancer Therapy.Frontiers in oral health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annu SinghDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0001-7066-4492
Evan B RosenDental Oncology and Maxillofacial Prosthetics, Miami Cancer Institute, Miami, Florida, USA.
Joseph D RandazzoDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Cherry L EstiloDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Daphna Y GelblumDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Joseph M HurynDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-7130-6264

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Intraoral radiation stents (IRS) are prosthetic devices that assist in the effective delivery of radiation to tumor tissues and aim to avoid unnecessary radiation to adjacent healthy tissues, thus limiting postradiotherapy toxicities. They are used to protect or displace vital structures, assist in positioning of the treatment beam for effective administration of radiotherapy, carry a radioactive material, shield healthy tissues of the oral cavity, and/or maintain the desired mouth opening during radiotherapy. With close collaboration between radiation oncologist and oral health care provider, several IRS can be fabricated by the latter for appropriate targeting and delivery of planned radiation dose and optimized treatment results. Modification of these IRS based on individual patient need is recommended to maximize prosthesis utility. The purpose of this review is to discuss the various types of IRS and highlight their clinical utility and benefits in patients receiving radiation therapy in the head and neck cancers.

Indexed as

Head and Neck NeoplasmsHumansMouthStentshead and neck cancerintraoral radiation stentradiation bite blockradiation mouthguardradiation therapy

Identifiers

PMID34480818
PMCPMC8595620

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.