Evidence map›Paper›PMID 34480785›Full record

Trial reportJournal of diabetes investigation2022

Comparison of the effects of frequent versus conventional nutritional interventions in patients with type 2 diabetes mellitus: A randomized, controlled trial.

Nao Kawabata, Kenta Okada, Akihiko Ando, Tomoyuki Kurashina, Manabu Takahashi, Tetsuji Wakabayashi, Daisuke Nagata, Eiji Kusano, Satsuki Mogi, Toshiko Sato and 2 more

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Education programmes for people with chronic kidney disease and diabetes.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Nao KawabataDepartment of Clinical Nutrition, Jichi Medical University Hospital, Shimotsuke, Japan.
Kenta OkadaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Akihiko AndoDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Tomoyuki KurashinaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Manabu TakahashiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Tetsuji WakabayashiDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Daisuke NagataDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Eiji KusanoDivision of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
Satsuki MogiDepartment of Clinical Nutrition, Jichi Medical University Hospital, Shimotsuke, Japan.
Toshiko SatoDepartment of Clinical Nutrition, Jichi Medical University Hospital, Shimotsuke, Japan.
Shizukiyo IshikawaMedical Education Center, Jichi Medical University, Shimotsuke, Japan.
Shun IshibashiDepartment of Clinical Nutrition, Jichi Medical University Hospital, Shimotsuke, Japan.ORCID https://orcid.org/0000-0002-1063-1979
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionThis randomized controlled trial aimed to determine whether frequent nutritional education improves the clinical parameters associated with the onset and progression of diabetic kidney disease in type 2 diabetes mellitus patients. MATERIALS AND

methodsA total of 96 patients with type 2 diabetes and diabetic kidney disease were randomly assigned to the intensive intervention group that received nutritional education at every outpatient visit, and the usual intervention group that received nutritional education once a year. The anthropometric parameters, blood pressure, blood chemistry, albuminuria, protein and salt intake, and prescribed medications of 87 patients who completed the 2-year follow up were analyzed.

resultsIn the intensive intervention group, body mass index and salt intake significantly decreased over the study period. Hemoglobin A1c levels and body fat percentage were significantly lower in the intensive intervention group than in the usual intervention group. At the end of the 2-year intervention period, the intensive intervention group had significantly lower salt intake (8.1 vs 9.4 g/day) than the usual intervention group. A significant positive correlation was found between salt intake and albuminuria in the overall group and intensive intervention group (r = 0.26, P = 0.02, and r = 0.36, P = 0.02, respectively). The intensive intervention group had a significantly lower insulin use rate than the usual intervention group after the 2-year intervention period (18% vs 42%). No differences were found in estimated glomerular filtration rate and albuminuria.

conclusionIntensive nutritional education is useful for alleviating the risk factors associated with the onset and progression of diabetic kidney disease.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesAlbuminuriaGlomerular Filtration RateGlycated HemoglobinHumansGlycated HemoglobinBody compositionHemoglobin A1cNutritional education

Identifiers

PMID34480785
PMCPMC8847137
OpenAlexW3197623442

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.