Evidence map›Paper›PMID 34480773›Full record

Trial reportThe International journal of eating disorders2021

A pilot randomized control trial of online exposure for eating disorders and mechanisms of change delivered after discharge from intensive eating disorder care: A registered report.

Cheri A Levinson, Christina Ralph-Nearman, Mackenzie L Brown, Taylor Gardner, Valentina Cardi, Janet Treasure, Kirstin Purves, Thalia C Eley

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cheri A LevinsonDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0002-8098-6943
Christina Ralph-NearmanDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0003-4989-153X
Mackenzie L BrownDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0002-9671-1223
Taylor GardnerDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.
Valentina CardiDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0002-7763-7099
Janet TreasureDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.
Kirstin PurvesDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.
Thalia C EleyDepartment of Psychological & Brain Sciences, University of Louisville, Louisville, Kentucky, USA.ORCID 0000-0001-6458-0700

Funding

Innovations in Personalizing Treatment for Eating Disorders Using Idiographic Methods and the Impact of Personalization on Psychological, Physical, and Sociodemographic OutcomesDP2MH136495 · NIMH · UNIVERSITY OF LOUISVILLE · PI Cheri Alicia Levinson · 2023 to 2026
$2.6M
A Pilot Randomized Control Trial of a Relapse Prevention Online Exposure Protocol for Eating Disorders and Mechanisms of ChangeR34MH124799 · NIMH · UNIVERSITY OF LOUISVILLE · PI LEVINSON, CHERI ALICIA · 2021 to 2023
$692k
Medical Research Council MR/V003283/1NIMH NIH HHS DP2 MH136495NIMH NIH HHS R34 MH124799NIMH NIH HHS R34MH124799
6 · The paper itself

Abstract

More than 50% of individuals with an eating disorder (ED) will readmit to treatment within 6 months of treatment discharge and often due to persistent cognitive ED pathology. Interventions addressing unremitted cognitive ED pathology following discharge from intensive treatment are crucial to prevent readmission. Imaginal exposure therapy facilitates the approach of feared stimuli not accessible in everyday life (e.g., rapidly gaining weight). In the current pilot randomized control trial (RCT), participants will be randomly assigned to a five-session online imaginal exposure condition (n = 65) or a control online writing and thinking intervention (n = 65) within a month of discharge from intensive treatment. Exposure participants write about and imagine an ED fear and control participants will write about their ED generally. We will examine the feasibility and acceptability of the treatment conditions and whether imaginal exposure is more effective in preventing readmission than the control condition. We will test the efficacy of the imaginal exposure treatment in reducing ED symptoms and fears of food and weight gain, and whether fear learning is a mechanism of change related to ED pathology. Ultimately, this research will lead to the development of an easily deployable readmission prevention treatment based on fear conditioning targets.

Indexed as

Feeding and Eating DisordersImplosive TherapyFearHumansPatient DischargePilot Projectseating disordersfear learningimaginal exposurerandomized controlled trial

Identifiers

PMID34480773
PMCPMC9886130

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.