Evidence map›Paper›PMID 34480707›Full record

ArticleJournal of natural medicines2022

Apigenin exerts chemopreventive effects on lung injury induced by SiO

Yajun Wang, Wenhui Chang, Xuezheng Li, Zhe Jiang, Di Zhou, Yuan Feng, Bingxin Li, Gang Chen, Ning Li

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of natural medicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yajun WangSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Wenhui ChangSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Xuezheng LiDepartment of PIVAS, Yanbian University Hospital, Yanji, China.
Zhe JiangDepartment of PIVAS, Yanbian University Hospital, Yanji, China.
Di ZhouSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Yuan FengSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Bingxin LiSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China.
Gang ChenSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China. chengang1152001@163.com.
Ning LiSchool of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang, 110016, China. liningsypharm@163.com.
Shenyang Pharmaceutical University · CNYanbian University Hospital · CNChinese Academy of Sciences · CN

Funding

doctoral scientific research foundation of liaoning province 2020-BS-129educational committee foundation of liaoning province 2020LJC09liaoning revitalization talents program XLYC1807118national natural science foundation of china 81872768national natural science foundation of china U1903122shenyang young scientific and technological innovators program RC200408special fund of research institute of drug regulatory science research shenyang pharmaceutical university 2021jgkx010state key laboratory for chemistry and molecular engineering of medicinal resources CMEMR2021-B01the fund of state key laboratory of phytochemistry and plant resources in west china P2020-KF01
6 · The paper itself

Abstract

Apigenin (APG) is a flavonoid widely distributed in fruits, vegetables, and herbs, with comprehensive pharmacological effects. In this paper, we report that APG can elicit a protective effect, which is comparable to those induced by gymnoside II/n-BuOH extracts of Bletilla striata, on SiO

Indexed as

Lung InjuryNanoparticlesApigeninApoptosisHumansNF-E2-Related Factor 2Oxidative StressReactive Oxygen SpeciesSignal TransductionSilicon DioxideApigeninNF-E2-Related Factor 2Reactive Oxygen SpeciesSilicon DioxideAPGChemopreventionLung injuryNm SiO2Nrf2

Identifiers

PMID34480707
OpenAlexW3196410193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.