Evidence map›Paper›PMID 34480649›Full record

SynthesisNeurosurgical review2022

Predictors of aneurysm occlusion following treatment with the WEB device: systematic review and case series.

Fadi Al Saiegh, Lohit Velagapudi, Omaditya Khanna, Ahmad Sweid, Nikolaos Mouchtouris, Michael P Baldassari, Thana Theofanis, Rizwan Tahir, Victoria Schunemann, Carrie Andrews and 8 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Balloon assisted Woven endobridge deployment (BAWD): A safety and efficacy study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Long-term efficacy and safety of WovenEndoBridge (WEB)-assisted cerebral aneurysm embolization.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Fadi Al Saiegh *Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Lohit Velagapudi *Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Omaditya KhannaDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Ahmad SweidDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Nikolaos MouchtourisDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Michael P BaldassariDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Thana TheofanisDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Rizwan TahirDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Victoria SchunemannDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Carrie AndrewsDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Lucas PhilippDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Nohra ChalouhiDepartment of Neurological Surgery, University of Florida, Gainesville, FL, USA.
Stavropoula I TjoumakarisDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
David HasanDepartment of Neurological Surgery, University of Iowa Hospitals, Iowa City, IA, USA.
M Reid GoochDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Nabeel A HerialDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Robert H RosenwasserDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Pascal JabbourDepartment of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA. Pascal.jabbour@jefferson.edu.ORCID http://orcid.org/0000-0002-8965-2413
Thomas Jefferson University · USUniversity of Florida · USUniversity of Iowa Hospitals and Clinics · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Woven EndoBridge (WEB) device is becoming increasingly popular for treatment of wide-neck aneurysms. As experience with this device grows, it is important to identify factors associated with occlusion following WEB treatment to guide decision making and screen patients at high risk for recurrence. The aim of this study was to identify factors associated with adequate aneurysm occlusion following WEB device treatment in the neurosurgical literature and in our case series. A systematic review of the present literature was conducted to identify studies related to the prediction of WEB device occlusion. In addition, a retrospective review of our institutional data for patients treated with the WEB device was performed. Demographics, aneurysm characteristics, procedural variables, and 6-month follow-up angiographic outcomes were recorded. Seven articles totaling 450 patients with 456 aneurysms fit our criteria. Factors in the literature associated with inadequate occlusion included larger size, increased neck width, partial intrasaccular thrombosis, irregular shape, and tobacco use. Our retrospective review identified 43 patients with 45 aneurysms. A total of 91.1% of our patients achieved adequate occlusion at a mean follow-up time of 7.32 months. Increasing degree of contrast stasis after WEB placement on the post-deployment angiogram was significantly associated with adequate occlusion on follow-up angiogram (p = 0.005) and with Raymond-Roy classification (p = 0.048), but not with retreatment (p = 0.617). In our systematic review and case series totaling 450 patients with 456 aneurysms, contrast stasis on post-deployment angiogram was identified as a predictor of adequate aneurysm occlusion, while morphological characteristics such as larger size and wide neck negatively impact occlusion.

Indexed as

Embolization, TherapeuticEndovascular ProceduresIntracranial AneurysmHumansRetrospective StudiesTreatment OutcomeAneurysmEndovascularOcclusionWEB device

Identifiers

PMID34480649
OpenAlexW3198914628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.