ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022
Risk Factors for Nonresilient Outcomes in Older Adults After Total Knee Replacement.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- An Exploratory Stability Selection (ESS) framework for robust predictor discovery: An application to physical resilience in aging populations.Experimental gerontology · 2026Article
- Lagged effects of risk factors on the disability of older adults: A distributed lag non-linear model approach.International journal of nursing sciences · 2026Article
- Development and external validation of a machine learning model for three-tier disability risk stratification in older adults.Frontiers in public health · 2026Article
- Resilience and Intrinsic Capacity in Older Adults: A Review of Recent Literature.Journal of clinical medicine · 2025Review
- Multivariate Profiling of Physical Resilience in Older Adults After Total Knee Replacement Surgery: Results From a Prospective Observational Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Observational
- From frailty to resilience: exploring adaptive capacity and reserve in older adults-a narrative review.Frontiers in aging · 2025Review
- Identifying predictors of resilience to stressors in single-arm studies of pre-post change.Biostatistics (Oxford, England) · 2024Article
- Development of the Clinical pHysical rEsilience assEssment Scale (CHEES) in Chinese Older Adults.The Journal of frailty & aging · 2024Review
- Graft failure within 2 years of isolated anterior cruciate ligament reconstruction is associated with increased risk of secondary meniscus tears.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- A Study of Physical Resilience and Aging (SPRING): Conceptual framework, rationale, and study design.Journal of the American Geriatrics Society · 2023Article
- Assessment of Physical Resilience Using Residual Methods and Its Association With Adverse Outcomes in Older Adults.Innovation in aging · 2023Article
- Physical Resilience Phenotype Trajectories in Incident Hemodialysis: Characterization and Mortality Risk Assessment.Kidney international reports · 2022Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTotal knee replacement (TKR) is a common procedure in older adults. Physical resilience may be a useful construct to explain variable outcomes. We sought to define a simple measure of physical resilience and identify risk factors for nonresilient patient outcomes.
methodsSecondary analysis of Function and Outcomes Research for Comparative Effectiveness in Total Joint Replacement (FORCE-TJR) cohort study, a prospective registry of total joint replacement. The analysis included 7 239 adults aged 60 or older who underwent TKR between 2011 and 2015. Measures included sociodemographic and health factors. Outcomes were categorized as physically resilient versus nonresilient based on the change from baseline to 1-year follow-up for 3 patient-reported outcomes: the physical component summary (PCS), bodily pain (BP), and vitality (VT) from the Short Form-36 subcomponent scores, at preop and 1-year postprocedure. Associations were expressed as relative risk (RR) of physically nonresilient outcomes using generalized linear regression models, with Poisson distribution and log link.
resultsAge, body mass index, and Charlson Comorbidity Index (CCI) were associated with increased risk of physically nonresilient outcomes across PCS, BP, and VT: age, per 5 years for PCS (RR = 1.18 [1.12-1.23]), BP (RR = 1.06 [1.01-1.11), and VT (RR = 1.09 [1.06-1.12]); body mass index, per 5 kg/m2, for PCS (RR = 1.13 [1.07-1.19]), BP (RR = 1.06 [1.00-1.11]), and VT (RR = 1.08 [1.04-1.11]); and CCI for PCS CCI = 1 (RR = 1.38 [1.20-1.59]), CCI = 2-5 (RR = 1.59 [1.35-1.88]), CCI ≥6 (RR = 1.55 [1.31-1.83]. Household income >$45 000 associated with lower risk for PCS (RR = 0.81 [0.70-0.93]), BP (RR = 0.80 [0.69-0.91]), and VT (RR = 0.86 [0.78-0.93]).
conclusionsWe operationalized physical resilience and identified factors predicting resilience after TKR. This approach may aid clinical risk stratification, guide further investigation of causes, and ultimately aid patients through the design of interventions to enhance physical resilience.
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