Evidence map›Paper›PMID 34480159›Full record

ArticleNature methods2021

Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution.

David Dierks, Miguel Angel Garcia-Campos, Anna Uzonyi, Modi Safra, Sarit Edelheit, Alice Rossi, Theodora Sideri, Radhika A Varier, Alexander Brandis, Yonatan Stelzer and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Optimized GLORI-Seq of Chromatin-Associated RNAs.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Single-molecule mbioRxiv : the preprint server for biology · 2026
    Article
  3. The relevance of mJournal of cancer research and clinical oncology · 2026
    Review
  4. Article
  5. The bladder cancer mEMBO reports · 2026
    Article
  6. Review
  7. Review
  8. High-stoichiometry mRNA (New York, N.Y.) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. FTO depletion does not alter mbioRxiv : the preprint server for biology · 2025
    Article
  17. NJournal of orthopaedic translation · 2025
    Review
  18. Article
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

David DierksDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Miguel Angel Garcia-CamposDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-5223-8174
Anna UzonyiDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Modi SafraDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Sarit EdelheitDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Alice RossiCell Fate and Gene Regulation Laboratory, The Francis Crick Institute, London, UK.
Theodora SideriCell Fate and Gene Regulation Laboratory, The Francis Crick Institute, London, UK.
Radhika A VarierCell Fate and Gene Regulation Laboratory, The Francis Crick Institute, London, UK.
Alexander BrandisLife Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Yonatan StelzerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Folkert van WervenCell Fate and Gene Regulation Laboratory, The Francis Crick Institute, London, UK.
Ruth Scherz-ShouvalDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-4570-121X
Schraga SchwartzDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. schwartz@weizmann.ac.il.ORCID http://orcid.org/0000-0002-3671-9709

Funding

Cancer Research UKMedical Research CouncilWellcome Trust FC001203
6 · The paper itself

Abstract

N

Indexed as

AdenosineAnimalsCell Cycle ProteinsGene ExpressionHalf-LifeMeiosisMethyltransferasesMiceMice, KnockoutMouse Embryonic Stem CellsRNA Splicing FactorsRNA StabilitySequence Analysis, RNAYeastsAdenosineCell Cycle ProteinsMethyltransferasesMettl3 protein, mouseN-methyladenosineRNA Splicing FactorsWtap protein, mouse

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.