ArticleInternational journal of retina and vitreous2021
Internal limiting membrane detachment in acute central retinal artery occlusion: a novel prognostic sign seen on OCT.
Article in International journal of retina and vitreous, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Time-, Location-, and Layer-Specific Chorioretinal Biomarkers in a Translational Large-Animal Porcine Model of Chorioretinal Ischemia.Investigative ophthalmology & visual science · 2026Article
- Internal limiting membrane detachment associated with papilloedema following brain metastasis in a child with Ewing sarcoma.Archive of clinical cases · 2025Article
- Internal limiting membrane separation and posterior vitreous hyperreflective dots: novel OCT findings in Purtscher-like retinopathy.BMC ophthalmology · 2024Article
- Retinal OCT findings in acute central retinal artery occlusion of varying severity at different disease stages - a retrospective, observational study.International journal of retina and vitreous · 2023Article
- Internal limiting membrane detachment in acute Central Retinal Artery Occlusion: clinical features, multimodal imaging, outcomes & prognostic biomarker.International journal of retina and vitreous · 2022Article
- Spectral Domain Optical Coherence Tomography Findings in Vision-Threatening Rhino-Orbital Cerebral Mucor Mycosis-A Prospective Analysis.Diagnostics (Basel, Switzerland) · 2022Article
- A review of the management of central retinal artery occlusion.Taiwan journal of ophthalmologyReview
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo present a series of acute central retinal artery occlusion (CRAO) cases showing internal limiting membrane detachment (ILMD) on optical coherence tomography (OCT) and to describe the possible etiopathogenesis and outcomes associated with it.
methodsDemographic and OCT features of patients with acute CRAO were analysed retrospectively. OCT parameters noted were posterior vitreous opacities, ILMD, inner retinal layer stratification, hyperreflectivity and thickening, cystoid macular edema, neurosensory detachment. Eyes were grouped into Group (1) CRAO with ILMD; Group (2) CRAO with no ILMD.
resultsA total of 28 eyes of acute CRAO who had undergone OCT scans at the time of the acute episode were identified. Out of these, ILMD was noted in 5 eyes. The study findings suggested that cases of acute CRAO with ILMD are associated with poor presenting visual acuity and have more severe signs of retinal hypoperfusion on OCT, like inner retinal thickening, inner retinal hyperreflectivity and loss of inner retinal layer stratification. Patients with ILMD have poor final visual acuity and thinning and atrophy or necrosis of the inner retinal layers.
conclusionILMD can occur in acute CRAO due to total retinal artery occlusion and severe retinal hypoperfusion. The presence of ILMD on OCT can be considered a sign of poor prognosis in cases of acute CRAO.
trial registrationNot applicable.
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