ArticleParticle and fibre toxicology2021
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.
Article in Particle and fibre toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Tuning photoactivity and photoprotection of TiORSC advances · 2026Article
- Engineering Mesoporous Silica Hosts for Ultrasmall ZnO Nanoparticles: A Dendritic Polymer-Assisted Strategy Towards Sustainable, Safe, and Effective Antibacterial Systems.Nanomaterials (Basel, Switzerland) · 2025Article
- Formation of Hybrid Spherical Silica Particles Using a Novel Alkoxy-Functional Polysilsesquioxane Macromonomer as a Precursor in an Acid-Catalyzed Sol-Gel Process.Materials (Basel, Switzerland) · 2025Article
- Influences of lead-based perovskite nanoparticles exposure on early development of human retina.Journal of nanobiotechnology · 2025Article
- SiOScientific reports · 2025Article
- Is Emerging Nanomedicine a Friend or Foe to Germ Cells?International journal of nanomedicine · 2025Review
- Construction and Biological Evaluation of Different Nanoshell Thickness Ni@SiOCurrent medicinal chemistry · 2025Article
- Effect ofRSC advances · 2024Article
- Fructose improves titanium dioxide nanoparticles induced alterations in developmental competence of mouse oocytes.BMC veterinary research · 2024Article
- Review of Zinc Oxide Nanoparticles: Toxicokinetics, Tissue Distribution for Various Exposure Routes, Toxicological Effects, Toxicity Mechanism in Mammals, and an Approach for Toxicity Reduction.Biological trace element research · 2024Review
- Phototoxic or Photoprotective?-Advances and Limitations of Titanium (IV) Oxide in Dermal Formulations-A Review.International journal of molecular sciences · 2023Review
- Fertility loss: negative effects of environmental toxicants on oogenesis.Frontiers in physiology · 2023Review
- Article
- The Impact of Metal Nanoparticles on Female Reproductive System: Risks and Opportunities.International journal of environmental research and public health · 2022Review
Corrections and comments
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMetal oxide nanoparticles (NPs) are increasingly used in many industrial and biomedical applications, hence their impact on occupational and public health has become a concern. In recent years, interest on the effect that exposure to NPs may exert on human reproduction has grown, however data are still scant. In the present work, we investigated whether different metal oxide NPs interfere with mouse cumulus cell-oocyte complex (COC) expansion.
methodsMouse COCs from pre-ovulatory follicles were cultured in vitro in the presence of various concentrations of two types of TiO
resultsWe show that COC expansion was not affected by the presence of both types of TiO
conclusionsAltogether, these results suggest that chemical composition, dissolution, and cell internalization are all responsible for the adverse effects of the tested NPs and support the importance of a tailored, safer-by-design production of NPs to reduce toxicity.
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