Evidence map›Paper›PMID 34479495›Full record

SynthesisBMC infectious diseases2021

A case report of rhino-facial mucormycosis in a non-diabetic patient with COVID-19: a systematic review of literature and current update.

Faezeh Mohammadi, Milad Badri, Shapoor Safari, Nima Hemmat

Open access · goldAbstract readCase ReportsSystematic Review
In one paragraph

Synthesis in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
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  6. An ubiquitous entity of post-COVID rhinomaxillary mucormycosis.Journal of family medicine and primary care · 2022
    Article
  7. Article
  8. Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Faezeh MohammadiDepartment of Medical Parasitology and Mycology, School of Medicine, Qazvin University of Medical Sciences, Shahid Bahonar Blvd, PO Box: 34199-15315, Qazvin, Iran. Faezehmohamadi119@yahoo.com.ORCID http://orcid.org/0000-0002-9822-2626
Milad BadriMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID http://orcid.org/0000-0002-1860-326X
Shapoor SafariDepartment of Otolaryngologist, Fellowship of Rhinology, Razi Hospital, Qazvin, Iran.
Nima HemmatDepartment of Cellular and Molecular Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
Qazvin University of Medical Sciences · IRRazi Hospital · IR

Funding

Qazvin University of Medical Sciences IR.QUMS.REC.1399.357
6 · The paper itself

Abstract

backgroundCOVID-19 disease may be associated with a wide range of bacterial and fungal infections. We report a patient with COVID-19 infection who developed rhino-facial mucormycosis during treatment with corticosteroids. CASE PRESENTATION: A 59-year-old non-diabetic male patient was admitted with a diagnosis of COVID-19 based on positive RT-PCR and CT of the lungs. Due to sever lung involvement, he was treated with methylprednisolone. The patient was re-admitted to hospital, due to nasal obstruction and left side facial and orbital swelling, several days after discharge. In sinus endoscopic surgery, debridement was performed and the specimens were sent to pathology and mycology laboratories. A nasal biopsy showed wide hyphae without septa. The sequenced PCR product revealed Rhizopus oryzae. Despite all medical and surgical treatment, the patient died. In addition, the characteristics of patients with COVID-19-associated mucormycosis were reviewed in 44 available literatures. In most studies, diabetes mellitus was the most common predisposing factor for mucormycosis.

conclusionOur report highlights the need for assessing the presence of mucormycosis in patients with COVID-19 and also it shows that physicians should consider the potential for secondary invasive fungal infections in COVID-19 cases.

Indexed as

COVID-19Diabetes MellitusInvasive Fungal InfectionsMucormycosisHumansMaleMiddle AgedSARS-CoV-2COVID-19MucormycosisRhizopus oryzae

Identifiers

PMID34479495
PMCPMC8415695
OpenAlexW3197732902

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.