ArticleThe journal of headache and pain2021
Flatness of the Meckel cave may cause primary trigeminal neuralgia: a radiomics-based study.
Article in The journal of headache and pain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Magnetic resonance imaging in the diagnosis of trigeminal neuralgia: a systematic review of the imaging protocol and diagnostic accuracy.European radiology · 2026Pooled it
- Current state of research and future developments of artificial intelligence in pain diagnosis and treatment.Journal of translational medicine · 2026Review
- Exploratory development of prediction models for pharmacotherapy outcomes in trigeminal neuralgia: a combined analysis based on multi-source data.The journal of headache and pain · 2026Article
- Radiomic Applications in Skull Base Pathology: A Systematic Review of Potential Clinical Uses.Journal of neurological surgery. Part B, Skull base · 2025Article
- Article
- A combined radiomics and anatomical features model enhances MRI-based recognition of symptomatic nerves in primary trigeminal neuralgia.Frontiers in neuroscience · 2024Article
- Multi-metric predictors of radiofrequency-treated trigeminal neuralgias.Brain communications · 2024Article
- Analyzing the risk factors of unilateral trigeminal neuralgia under neurovascular compression.Frontiers in human neuroscience · 2024Article
- Association between morphological characteristics of Meckel's cave and outcomes after percutaneous balloon compression for primary trigeminal neuralgia.Neurosurgical review · 2023Article
- The Consistency Between the Preoperative 3D-Reconstructed Meckel's Cave and the Intraoperative Balloon Results in Percutaneous Balloon Compression.Journal of pain research · 2023Article
- Absence of Meckel's Cave with Trigeminal Neuralgia: A Case Report.The Indian journal of radiology & imaging · 2023Article
- Article
- Identifying symptomatic trigeminal nerves from MRI in a cohort of trigeminal neuralgia patients using radiomics.Neuroradiology · 2022Article
- Narrow ovale foramina may be involved in the development of primary trigeminal neuralgia.Frontiers in neurology · 2022Article
- Combination of Preoperative Multimodal Image Fusion and Intraoperative Dyna CT in Percutaneous Balloon Compression of Trigeminal Ganglion for Primary Trigeminal Neuralgia: Experience in 24 Patients.Frontiers in surgery · 2022Article
- Risk Factors for Unilateral Trigeminal Neuralgia Based on Machine Learning.Frontiers in neurology · 2022Article
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5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundNeurovascular contact (NVC) is the main cause of primary trigeminal neuralgia (PTN); however, cases of PTN without NVC are still observed. In this study, the Meckel cave (MC) morphology in PTN were analyzed by radiomics and compared to healthy controls (HCs) to explore the cause of PTN.
methodsWe studied the 3.0T MRI data of 115 patients with PTN and 46 HCs. Bilateral MC was modeled using the 3D Slicer software, and the morphological characteristics of MC were analyzed using the radiomics method.
resultsThe right side incidence rate in the PTN group was higher than the left side incidence. By analyzing the flatness feature of MC, we observed that the affected side of the PTN was lower than that of the unaffected side, the right MC of the PTN and HC was lower than that of the left MC, the MC of the affected side of the left and right PTN without bilateral NVC was lower than that of the unaffected side.
conclusionsBy providing a method to analyze the morphology of the MC, we found that there is an asymmetry in the morphology of bilateral MC in the PTN and HC groups. It can be inferred that the flatness of the MC may be a cause of PTN.
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