Evidence map›Paper›PMID 34479220›Full record

ArticleBiofabrication2021

miRNA induced co-differentiation and cross-talk of adipose tissue-derived progenitor cells for 3D heterotypic pre-vascularized bone formation.

Nazmiye Celik, Myoung Hwan Kim, Daniel J Hayes, Ibrahim T Ozbolat

Open access · greenAbstract read
In one paragraph

Article in Biofabrication, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Bioprinting of miRNA-Induced Spheroids for Vascularized, Heterocellular Bone Regeneration.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nazmiye CelikDepartment of Engineering Science and Mechanics, Pennsylvania State University, 212 Earth-Engineering Sciences Bldg., University Park, PA 16802, United States of America.
Myoung Hwan KimThe Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, United States of America.
Daniel J HayesThe Huck Institutes of the Life Sciences, Penn State University, University Park, PA 16802, United States of America.
Ibrahim T OzbolatDepartment of Engineering Science and Mechanics, Pennsylvania State University, 212 Earth-Engineering Sciences Bldg., University Park, PA 16802, United States of America.ORCID 0000-0001-8328-4528
Pennsylvania State University · US

Funding

Intraoperative bioprinting of composite tissues with zonal stratification for craniomaxillofacial reconstructionR01DE028614 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI OZBOLAT, IBRAHIM · 2020 to 2024
$2.8M
Spatiotemporal Modulation of Osteogenesis in a 3-D Stromal/Stem Cell ModelR01DE024790 · NIDCR · PENNSYLVANIA STATE UNIVERSITY, THE · PI HAYES, DANIEL J. · 2015 to 2019
$1.7M
NIDCR NIH HHS R01 DE024790NIDCR NIH HHS R01 DE028614
6 · The paper itself

Abstract

Engineered bone grafts require a vascular network to supply cells with oxygen, nutrients and remove waste. Using heterotypic mature cells to create these grafts

Indexed as

Adipose TissueCell DifferentiationOsteogenesisStem CellsMicroRNAsTissue EngineeringTissue ScaffoldsMicroRNAsbioprintingbonemiRNApre-vascularizationspheroid assemblystem cells

Identifiers

PMID34479220
PMCPMC8596330
OpenAlexW3198088481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.