Evidence map›Paper›PMID 34479111›Full record

GuidelineMultiple sclerosis and related disorders2021

MENACTRIMS practice guideline for COVID-19 vaccination in patients with multiple sclerosis.

Bassem I Yamout, Magd Zakaria, Jihad Inshasi, Mohammad Al-Jumah, Maya Zeineddine, Maurice Dahdaleh, Saeed Bohlega, Riadh Gouider, Raed Alroughani

Open access · bronzeAbstract readReviewPractice Guideline
In one paragraph

Guideline in Multiple sclerosis and related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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  7. Incidence of SARS-CoV-2 infection in patients with multiple sclerosis who received SARS-CoV-2 vaccines and are under treatment with high-efficacy therapies in Argentina.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 6 countries.

Bassem I YamoutNeurology Institute and Multiple Sclerosis Center, Harley Street Medical Center, Abu Dhabi, United Arab Emirates.
Magd ZakariaAin Shams University, Cairo, Egypt.
Jihad InshasiDepartment of Neurology, Rashid Hospital and Dubai Medical College, Dubai Health Authority, Dubai, United Arab Emirates.
Mohammad Al-JumahKing Fahad Medical City, MOH, Riyadh, Saudi Arabia.
Maya ZeineddineNeurology Institute and Multiple Sclerosis Center, Harley Street Medical Center, Abu Dhabi, United Arab Emirates. Electronic address: mzeineddine39@mail.com.
Maurice DahdalehAl Khalidi Hospital, Amman, Jordan.
Saeed BohlegaKing Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Riadh GouiderService de Neurologie, Hôpital Razi, Manouba, Tunisia.
Raed AlroughaniAmiri Hospital, Arabian Gulf Street, Sharq, Kuwait.
Ain Shams University · EGAmiri Hospital · KWHôpital Razi de La Manouba · TNJordan Hospital · JOKing Fahd Medical City · SAKing Faisal Specialist Hospital & Research Centre · SARashid Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with multiple sclerosis (MS) should be vaccinated against COVID-19. All COVID-19 vaccines are effective and do not appear to carry any additional risk for patients with MS. Patients with MS should get a COVID-19 vaccine as soon as it becomes available. The risks of COVID-19 disease outweigh any potential risks from the vaccine. Even if vaccinated, patients with MS should continue to practice standard and recommended precautions against COVID-19, such as wearing a face mask, social distancing and washing hands. There is no evidence that patients with MS are at higher risk of complications from the mRNA, non-replicating viral vector, inactivated virus or protein COVID-19 vaccines, compared to the general population. COVID-19 Vaccines are safe to use in patients with MS treated with disease-modifying therapies (DMTs). The effectiveness of vaccination may be affected by few of the DMTs but yet some protection is still provided. For certain DMTs we may consider coordinating the timing of the vaccine with the timing of the DMT dose to increase vaccine efficacy.

Indexed as

COVID-19Multiple SclerosisCOVID-19 VaccinesHumansSARS-CoV-2VaccinationVaccine EfficacyCOVID-19 VaccinesCOVID-19Disease-modifying therapiesMultiple sclerosisSARS-CoV-2Vaccines

Identifiers

PMID34479111
PMCPMC8386106
OpenAlexW3195389527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.