Evidence map›Paper›PMID 34478955›Full record

ArticleVirology2021

Upregulation of FOXP3 is associated with severity of hypoxia and poor outcomes in COVID-19 patients.

Ahmed S Abdelhafiz, Mariam A Fouad, Mohamed M Sayed-Ahmed, Mahmoud M Kamel, Asmaa Ali, Merhan Fouda, Mahmoud A Khalil, Ahmed S Abdel-Moneim, Lamyaa M Kamal

Open access · greenAbstract read
In one paragraph

Article in Virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Ahmed S AbdelhafizDepartment of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
Mariam A FouadPharmacology and Experimental Oncology Unit, National Cancer Institute, Cairo University, Cairo, Egypt; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, PA, USA.
Mohamed M Sayed-AhmedPharmacology and Experimental Oncology Unit, National Cancer Institute, Cairo University, Cairo, Egypt.
Mahmoud M KamelDepartment of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
Asmaa AliDepartment of Pulmonary Medicine, Abbassia Chest Hospital, MOH, Cairo, Egypt.
Merhan FoudaDepartment of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
Mahmoud A KhalilDepartment of Tropical Medicine and Infectious Disease, Imbaba Fever Hospital, MOH, Cairo, Egypt.
Ahmed S Abdel-MoneimMicrobiology Department, College of Medicine, Taif University, P.O. Box 1109, Taif, 21944, Saudi Arabia. Electronic address: asa@tu.edu.sa.
Lamyaa M KamalDepartment of Clinical and Chemical Pathology, Elsahel Teaching Hospital, MOH, Cairo, Egypt.
Cairo University · EGFox Chase Cancer Center · USResearch Institute of Ophthalmology · EGTaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The levels of messenger RNA (mRNA) transcription of FOXP3, IFN-γ, TNF, IL-6 and COX-2 from both COVID-19 infected and control subjects were evaluated using SYBR

Indexed as

AdultCOVID-19CytokinesFemaleForkhead Transcription FactorsHumansHypoxiaMaleMiddle AgedRNA, MessengerSeverity of Illness IndexCytokinesForkhead Transcription FactorsFOXP3 protein, humanRNA, MessengerCOVID-19COX-2FOXP3IFN-γIL-6PrognosisSARS-CoV-2TNFα

Identifiers

PMID34478955
PMCPMC8397927
OpenAlexW3197800763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.