Evidence map›Paper›PMID 34478675›Full record

ArticleThe Lancet. Oncology2021

Radiotherapy resources in Africa: an International Atomic Energy Agency update and analysis of projected needs.

Shekinah N C Elmore, Alfredo Polo, Jean-Marc Bourque, Yaroslav Pynda, Debbie van der Merwe, Surbhi Grover, Kirsten Hopkins, Eduardo Zubizarreta, May Abdel-Wahab

Open access · greenAbstract read
In one paragraph

Article in The Lancet. Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 4 pooled it
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Barriers to Radiotherapy Access in Sub-Saharan Africa for Patients with Cancer: A Systematic Review.International journal of environmental research and public health · 2024
    Pooled it
  3. Pooled it
  4. Cervical cancer survival times in Africa.Frontiers in public health · 2022
    Pooled it
  5. Article
  6. Does One Size Fit All? Commentary on the HYPNO Trial.International journal of radiation oncology, biology, physics · 2026
    Article
  7. Article
  8. Article
  9. [Survey of radiotherapy resource allocation and service capacity in Hunan Province, 2025].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  10. Quantitative analysis of trends and inequalities in disease burden and care quality of gynecological cancers, 1990-2021.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Shekinah N C ElmoreDepartment of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Harvard Radiation Oncology Program, Boston, MA, USA.
Alfredo PoloDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
Jean-Marc BourqueDivision of Radiation Oncology, University of Ottawa, Ottawa, ON, Canada; Department of Medicine, McGill University, Montreal, QC, Canada.
Yaroslav PyndaDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
Debbie van der MerweDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
Surbhi GroverDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Kirsten HopkinsDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
Eduardo ZubizarretaDivision of Human Health, International Atomic Energy Agency, Vienna, Austria.
May Abdel-WahabDivision of Human Health, International Atomic Energy Agency, Vienna, Austria. Electronic address: m.abdel-wahab@iaea.org.
International Atomic Energy Agency · ATUniversity of Pennsylvania · US

Funding

Prognostic value of quantitative HPV viral load in determining cervical cancer treatment response and recurrenceK08CA230170 · NCI · UNIVERSITY OF PENNSYLVANIA · PI GROVER, SURBHI · 2019 to 2023
$1.4M
NCI NIH HHS K08 CA230170
6 · The paper itself

Abstract

The number of patients with cancer in Africa has been predicted to increase from 844 279 in 2012 to more than 1·5 million in 2030. However, many countries in Africa still lack access to radiotherapy as a part of comprehensive cancer care. The objective of this analysis is to present an updated overview of radiotherapy resources in Africa and to analyse the gaps and needs of the continent for 2030 in the context of the UN Sustainable Development Goals. Data from 54 African countries on teletherapy megavoltage units and brachytherapy afterloaders were extracted from the Directory for Radiotherapy Centres, an electronic, centralised, and continuously updated database of radiotherapy centres. Cancer incidence and future predictions were taken from the GLOBOCAN 2018 database of the International Agency for Research on Cancer. Radiotherapy need was estimated using a 64% radiotherapy utilisation rate, while assuming a machine throughput of 500 patients per year. As of March, 2020, 28 (52%) of 54 countries had access to external beam radiotherapy, 21 (39%) had brachytherapy capacity, and no country had a capacity that matched the estimated treatment need. Median income was an important predictor of the availability of megavoltage machines: US$1883 (IQR 914-3269) in countries without any machines versus $4485 (3079-12480) in countries with at least one megavoltage machine (p=0·0003). If radiotherapy expansion continues at the rate observed over the past 7 years, it is unlikely that the continent will meet its radiotherapy needs. This access gap might impact the ability to achieve the Sustainable Development Goals, particularly the target to reduce preventable, premature mortality by a third, and meet the target of the cervical cancer elimination strategy of 90% with access to treatment. Urgent, novel initiatives in financing and human capacity building are needed to change the trajectory and provide comprehensive cancer care to patients in Africa in the next decade.

Indexed as

AfricaForecastingHealth ResourcesHealth Services Needs and DemandHumansInternational AgenciesNeoplasmsRadiotherapySustainable Development

Identifiers

PMID34478675
PMCPMC8675892
OpenAlexW3197518149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.