Evidence map›Paper›PMID 34478664›Full record

ArticleThe Lancet. Oncology2021

Pembrolizumab monotherapy for high-risk, non-muscle invasive bladder cancer - Authors' reply.

Arjun V Balar, Ashish M Kamat, Ronald de Wit, KEYNOTE-057 investigators

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in The Lancet. Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. FDA Approval Summary: Nogapendekin Alfa Inbakicept-pmln with BCG for BCG-Unresponsive Carcinoma In Situ.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  2. Review of BCG immunotherapy for bladder cancer.Clinical microbiology reviews · 2025
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Arjun V BalarLaura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016, USA. Electronic address: arjun.balar@nyulangone.org.
Ashish M KamatMD Anderson Cancer Center, University of Texas, Houston, TX, USA.
Ronald de WitErasmus University Medical Center, Rotterdam, Netherlands.
KEYNOTE-057 investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Agents, ImmunologicalUrinary Bladder NeoplasmsAntibodies, Monoclonal, HumanizedHumansAntibodies, Monoclonal, HumanizedAntineoplastic Agents, Immunologicalpembrolizumab

Identifiers

PMID34478664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.