Evidence map›Paper›PMID 34478644›Full record

ArticleCurrent biology : CB2021

Mechanosensory input during circuit formation shapes Drosophila motor behavior through patterned spontaneous network activity.

Arnaldo Carreira-Rosario, Ryan A York, Minseung Choi, Chris Q Doe, Thomas R Clandinin

Open access · greenAbstract read
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

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  4. ImmatureProceedings of the National Academy of Sciences of the United States of America · 2026
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  7. ImmaturebioRxiv : the preprint server for biology · 2025
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  16. Developmentally Unique Cerebellar Processing Prioritizes Self- over Other-Generated Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Arnaldo Carreira-RosarioDepartment of Neurobiology, Stanford University, Stanford, CA 94305, USA; Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, OR 97403, USA.
Ryan A YorkDepartment of Neurobiology, Stanford University, Stanford, CA 94305, USA.
Minseung ChoiDepartment of Neurobiology, Stanford University, Stanford, CA 94305, USA.
Chris Q DoeInstitute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, OR 97403, USA. Electronic address: cdoe@uoregon.edu.
Thomas R ClandininDepartment of Neurobiology, Stanford University, Stanford, CA 94305, USA. Electronic address: trc@stanford.edu.
Howard Hughes Medical Institute · USStanford University · USStanford Medicine · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI TIRIN MOORE · 2017 to 2026
$8.0M
GENETIC AND MOLECULAR STUDIES OF NEUROGENESISR01HD027056 · NICHD · UNIVERSITY OF OREGON · PI Chris Q Doe · 1989 to 2026
$5.0M
Genetic and Molecular Studies of NeurogenesisR37HD027056 · NICHD · UNIVERSITY OF OREGON · PI DOE, CHRIS Q · 2012 to 2021
$3.0M
Structure and function of spontaneous network activity during circuit formationK99NS119295 · NINDS · STANFORD UNIVERSITY · PI CARREIRA-ROSARIO, ARNALDO · 2021 to 2022
$211k
The role of patterned spontaneous network activity in motor circuit activityF32NS105350 · NINDS · UNIVERSITY OF OREGON · PI CARREIRA-ROSARIO, ARNALDO · 2018 to 2020
$129k
Howard Hughes Medical InstituteNEI NIH HHS P30 EY026877NICHD NIH HHS R01 HD027056NICHD NIH HHS R37 HD027056NIH HHS P40 OD018537NINDS NIH HHS F32 NS105350NINDS NIH HHS K99 NS119295
6 · The paper itself

Abstract

Neural activity sculpts circuit wiring in many animals. In vertebrates, patterned spontaneous network activity (PaSNA) generates sensory maps and establishes local circuits.

Indexed as

DrosophilaSynaptic TransmissionAnimalsLarvaMuscle ContractionNeuronsbehavioral developmentdevelopment of locomotor behaviorDrosophila embryonervous system developmentneural circuit wiringspontaneous network activity

Identifiers

PMID34478644
PMCPMC8665011
OpenAlexW3197902487

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.