Healing takes nerve.

Emily Scott-Solomon, Yulia Shwartz, Ya-Chieh Hsu

Abstract readComment

In one paragraph

Article in Cell stem cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Lipid alterations in hereditary peripheral neuropathies: common mechanisms in disease heterogeneity?Molecular neurodegeneration · 2026
Review
Immunomodulatory Nanosystems: Advanced Delivery Tools for Treating Chronic Wounds.Research (Washington, D.C.) · 2023
Review

4 · The record

Corrections and comments

Comment on
Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization.2021

5 · Who and what money

Authors and funding

3 authors.

Emily Scott-SolomonDepartment of Stem Cell and Regenerative Biology, Harvard University, MA 02138, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.

Yulia ShwartzDepartment of Stem Cell and Regenerative Biology, Harvard University, MA 02138, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.

Ya-Chieh HsuDepartment of Stem Cell and Regenerative Biology, Harvard University, MA 02138, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA. Electronic address: yachieh_hsu@harvard.edu.

Funding

Nerve-stem cell interactions during skin homeostasis and wound repairF32AR079252 · NIAMS · HARVARD UNIVERSITY · PI SCOTT-SOLOMON, EMILY RIVKAH · 2021 to 2023

$205k

NIAMS NIH HHS F32 AR079252

6 · The paper itself

Abstract

Epidermal stem cells display remarkable capacities to restore the barrier upon skin injury. In this issue of Cell Stem Cell, Huang et al. (2021) use innovative high-resolution intravital imaging to identify a vital function of sensory nerves in regulating a subset of epidermal stem cells for wound repair.

Indexed as

Nerve TissueWound HealingEpidermal CellsStem Cells

Identifiers

PMID34478625

DOI10.1016/j.stem.2021.08.009

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.