ArticleInternational journal of clinical practice2021
An association between immune status and chest CT scores in COVID-19 patients.
Article in International journal of clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Development and external validation of a prognostic tool for nonsevere COVID-19 inpatients.Epidemiology and infection · 2023Article
- An association between immune status and chest CT scores in COVID-19 patients.International journal of clinical practice · 2021Article
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
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Abstract
backgroundThe characteristic features of the immune responses of COVID-19 patients and how they reflect lung involvement have not been clearly elucidated.
aimThe aim of this study was to examine the immune status and the correlations thereof with chest CT scores and lung involvement of patients with COVID-19.
methodsIn this retrospective and single-center study, 72 patients with laboratory-confirmed COVID-19 were recruited. The counts of peripheral lymphocyte subsets (CD3
resultsThe proportions of lymphopenia in patients with extensive lung involvement were twice that in the general study population. In the severe disease group, the levels of total lymphocytes, T cells, B cells, NK cells; and serum IgA levels, were significantly lower than in the mild disease group (all P < .05). We found that the numbers of lymphocyte subsets and the IgA level negatively correlated with the chest CT scores. On multivariate regression analysis, pretreatment decreases in total lymphocytes, CD3
conclusionsThe cell numbers of peripheral lymphocyte subsets and the serum IgA level were negatively correlated with the chest CT scores in COVID-19 patients. These parameters tended to independently predict severe lung involvement in such patients.
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