Evidence map›Paper›PMID 34478499›Full record

ArticleDatabase : the journal of biological databases and curation2021

Peptipedia: a user-friendly web application and a comprehensive database for peptide research supported by Machine Learning approach.

Cristofer Quiroz, Yasna Barrera Saavedra, Benjamín Armijo-Galdames, Juan Amado-Hinojosa, Álvaro Olivera-Nappa, Anamaria Sanchez-Daza, David Medina-Ortiz

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  9. Peptipedia v2.0: a peptide sequence database and user-friendly web platform. A major update.Database : the journal of biological databases and curation · 2024
    Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristofer QuirozFacultad de Ingeniería, Universidad Autonóma de Chile, Cinco Pte. 1670, Talca 3467987, Chile.
Yasna Barrera SaavedraEscuela de Ingeniería en Bioinformática, Universidad de Talca, Avenida Lircay SN, Talca 3460000, Chile.
Benjamín Armijo-GaldamesCentre for Biotechnology and Bioengineering, Universidad de Chile, Beauchef 851, Santiago 8370448, Chile.
Juan Amado-HinojosaCentre for Biotechnology and Bioengineering, Universidad de Chile, Beauchef 851, Santiago 8370448, Chile.
Álvaro Olivera-NappaCentre for Biotechnology and Bioengineering, Universidad de Chile, Beauchef 851, Santiago 8370448, Chile.
Anamaria Sanchez-DazaCentre for Biotechnology and Bioengineering, Universidad de Chile, Beauchef 851, Santiago 8370448, Chile.ORCID 0000-0002-6769-3281
David Medina-OrtizCentre for Biotechnology and Bioengineering, Universidad de Chile, Beauchef 851, Santiago 8370448, Chile.ORCID 0000-0002-8369-5746

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides have attracted attention during the last decades due to their extraordinary therapeutic properties. Different computational tools have been developed to take advantage of existing information, compiling knowledge and making available the information for common users. Nevertheless, most related tools available are not user-friendly, present redundant information, do not clearly display the data, and usually are specific for particular biological activities, not existing so far, an integrated database with consolidated information to help research peptide sequences. To solve these necessities, we developed Peptipedia, a user-friendly web application and comprehensive database to search, characterize and analyse peptide sequences. Our tool integrates the information from 30 previously reported databases with a total of 92 055 amino acid sequences, making it the biggest repository of peptides with recorded activities to date. Furthermore, we make available a variety of bioinformatics services and statistical modules to increase our tool's usability. Moreover, we incorporated a robust assembled binary classification system to predict putative biological activities for peptide sequences. Our tools' significant differences with other existing alternatives become a substantial contribution for developing biotechnological and bioengineering applications for peptides. Peptipedia is available for non-commercial use as an open-access software, licensed under the GNU General Public License, version GPL 3.0. The web platform is publicly available at peptipedia.cl. Database URL: Both the source code and sample data sets are available in the GitHub repository https://github.com/ProteinEngineering-PESB2/peptipedia.

Indexed as

Computational BiologySoftwareDatabases, FactualMachine LearningPeptidesPeptides

Identifiers

PMID34478499
PMCPMC8415426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.