Evidence map›Paper›PMID 34478358›Full record

ArticleAmerican journal of respiratory and critical care medicine2021

The Epigenomic Landscape: A Cornerstone of Macrophage Phenotype Regulation in the Fibrotic Lung.

Megan N Ballinger, Ana L Mora

Abstract readEditorialComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mechanisms and markers of lung ageing in health and disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  2. Review
  3. Macrophages and Pulmonary Fibrosis.Current molecular medicine · 2025
    Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Megan N BallingerDivision of Pulmonary, Critical Care and Sleep Medicine and Dorothy M. Davis Heart and Lung Research Institute The Ohio State University Columbus, Ohio.
Ana L MoraDivision of Pulmonary, Critical Care and Sleep Medicine and Dorothy M. Davis Heart and Lung Research Institute The Ohio State University Columbus, Ohio.ORCID 0000-0003-1653-8318

Funding

The pivotal role of macrophages in regulating pulmonary fibrosisR01HL141217 · NHLBI · OHIO STATE UNIVERSITY · PI BALLINGER, MEGAN N · 2019 to 2023
$2.5M
Mapping Age-Related Changes in the LungU01HL145550 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BENOS, PANAGIOTIS V, FINKEL, TOREN · 2019 to 2022
$2.4M
NHLBI NIH HHS R01 HL141217NHLBI NIH HHS U01 HL145550
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EpigenomicsPulmonary FibrosisHumansLungMacrophagesPhenotype

Identifiers

PMID34478358
PMCPMC8534622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.