Evidence map›Paper›PMID 34477990›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021

Critical illness neuropathy in severe COVID-19: a case series.

Tommaso Bocci, Laura Campiglio, Manuela Zardoni, Stefano Botta, Silvia Coppola, Elisabetta Groppo, Davide Chiumello, Alberto Priori

Open access · bronzeAbstract read
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Observational
  2. Review
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  8. Peripheral Neuropathy Evaluations of Patients With Prolonged Long COVID.Neurology(R) neuroimmunology & neuroinflammation · 2022
    Article
  9. Review
  10. Reply to "Digging deeper on the neurophysiological assessment in COVID-19 patients" and "Myopathy in acute and long-term COVID-19".Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022
    Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Tommaso BocciAldo Ravelli" Center for Neurotechnology and Experimental Brain Therapeutics, Department of Health Sciences, University of Milan, Milan, Italy.
Laura CampiglioClinical Neurology Unit, ASST Santi Paolo & Carlo, Milan, Italy.
Manuela ZardoniClinical Neurology Unit, ASST Santi Paolo & Carlo, Milan, Italy.
Stefano BottaClinical Neurology Unit, ASST Santi Paolo & Carlo, Milan, Italy.
Silvia CoppolaIntensive Care, Anesthesia and Resuscitation Unit, ASST Santi Paolo & Carlo, Milan, Italy.
Elisabetta GroppoClinical Neurology Unit, ASST Santi Paolo & Carlo, Milan, Italy.
Davide ChiumelloIntensive Care, Anesthesia and Resuscitation Unit, ASST Santi Paolo & Carlo, Milan, Italy.
Alberto PrioriAldo Ravelli" Center for Neurotechnology and Experimental Brain Therapeutics, Department of Health Sciences, University of Milan, Milan, Italy. alberto.priori@unimi.it.ORCID http://orcid.org/0000-0002-1549-3851
Ospedale San Paolo · ITUniversity of Milan · ITAOL (United States) · US

Funding

Fondazione Romeo ed Enrica Invernizzi Bando Covid 2019
6 · The paper itself

Abstract

introductionNeurological complications of SARS-CoV-2 disease have received growing attention, but only few studies have described to date clinical and neurophysiological findings in COVID patients during their stay in intensive care units (ICUs). Here, we neurophysiologically assessed the presence of either critical illness neuropathy (CIP) or myopathy (CIM) in ICU patients. MATERIALS AND

methodsPatients underwent a neurophysiological assessment, including bilateral examination of the median, ulnar, deep peroneal and tibial motor nerves and of the median, ulnar, radial and sural sensory nerves. Needle electromyography (EMG) was performed for both distal and proximal muscles of the lower and upper limbs. In order to differentiate CIP from CIM, Direct Muscle Stimulation (DMS) was applied either to the deltoid or tibialis anterior muscles. Peak to peak amplitudes and onset latencies of the responses evoked by DMS (DMS

resultsNerve conduction studies showed a sensory-motor polyneuropathy with axonal neurogenic pattern, as confirmed by needle EMG. Both MNS

conclusionsWe have described COVID patients in the ICU with critical illness neuropathy (CIP). COVID-related CIP could have implications for the functional recovery and rehabilitation strategies.

Indexed as

COVID-19Muscular DiseasesPolyneuropathiesCritical IllnessElectromyographyHumansNeural ConductionSARS-CoV-2COVID-19Critical illness myopathyCritical illness neuropathyNeurophysiologySARS-CoV-2

Identifiers

PMID34477990
PMCPMC8414960
OpenAlexW3196823935

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.