Evidence map›Paper›PMID 34477562›Full record

ArticleJournal of medical Internet research2021

Evaluation of Changes in Depression, Anxiety, and Social Anxiety Using Smartphone Sensor Features: Longitudinal Cohort Study.

Jonah Meyerhoff, Tony Liu, Konrad P Kording, Lyle H Ungar, Susan M Kaiser, Chris J Karr, David C Mohr

Open access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 9 pooled it
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 9 syntheses or guidelines pooled it, 84 citations in OpenAlex.

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  8. A Systematic Review of Location Data for Depression Prediction.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jonah MeyerhoffCenter for Behavioral Intervention Technologies, Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-5149-7959
Tony LiuDepartment of Computer and Information Science, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0002-3707-3989
Konrad P KordingDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0001-8408-4499
Lyle H UngarDepartment of Computer and Information Science, University of Pennsylvania, Philadelphia, PA, United States.ORCID 0000-0003-2047-1443
Susan M KaiserCenter for Behavioral Intervention Technologies, Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-5749-2072
Chris J KarrAudacious Software, Chicago, IL, United States.ORCID 0000-0003-1828-4497
David C MohrCenter for Behavioral Intervention Technologies, Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-5443-7596
Northwestern University · USUniversity of Pennsylvania · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Technology Enabled Services for Coordinated Care of Depression in Healthcare SettingsP50MH119029 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Rachel Kornfield · 2020 to 2026
$10.7M
LifeSense: Transforming Behavioral Assessment of Depression Using Personal Sensing TechnologyR01MH111610 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KORDING, KONRAD P., MOHR, DAVID CURTIS · 2017 to 2020
$3.2M
Multidisciplinary Training Program in Digital Mental HealthT32MH115882 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Darren Gergle, DAVID CURTIS MOHR · 2018 to 2026
$2.4M
NCATS NIH HHS UL1 TR001422NIMH NIH HHS P50 MH119029NIMH NIH HHS R01 MH111610NIMH NIH HHS T32 MH115882
6 · The paper itself

Abstract

backgroundThe assessment of behaviors related to mental health typically relies on self-report data. Networked sensors embedded in smartphones can measure some behaviors objectively and continuously, with no ongoing effort.

objectiveThis study aims to evaluate whether changes in phone sensor-derived behavioral features were associated with subsequent changes in mental health symptoms.

methodsThis longitudinal cohort study examined continuously collected phone sensor data and symptom severity data, collected every 3 weeks, over 16 weeks. The participants were recruited through national research registries. Primary outcomes included depression (8-item Patient Health Questionnaire), generalized anxiety (Generalized Anxiety Disorder 7-item scale), and social anxiety (Social Phobia Inventory) severity. Participants were adults who owned Android smartphones. Participants clustered into 4 groups: multiple comorbidities, depression and generalized anxiety, depression and social anxiety, and minimal symptoms.

resultsA total of 282 participants were aged 19-69 years (mean 38.9, SD 11.9 years), and the majority were female (223/282, 79.1%) and White participants (226/282, 80.1%). Among the multiple comorbidities group, depression changes were preceded by changes in GPS features (Time: r=-0.23, P=.02; Locations: r=-0.36, P<.001), exercise duration (r=0.39; P=.03) and use of active apps (r=-0.31; P<.001). Among the depression and anxiety groups, changes in depression were preceded by changes in GPS features for Locations (r=-0.20; P=.03) and Transitions (r=-0.21; P=.03). Depression changes were not related to subsequent sensor-derived features. The minimal symptoms group showed no significant relationships. There were no associations between sensor-based features and anxiety and minimal associations between sensor-based features and social anxiety.

conclusionsChanges in sensor-derived behavioral features are associated with subsequent depression changes, but not vice versa, suggesting a directional relationship in which changes in sensed behaviors are associated with subsequent changes in symptoms.

Indexed as

DepressionSmartphoneAdultAnxietyAnxiety DisordersFemaleHumansLongitudinal StudiesMaleanxietydepressiondigital biomarkersdigital phenotypingecological momentary assessmentinternet technologymental health assessmentmHealthmobile devicemobile phonepassive sensingpersonal sensingpsychiatric disorders

Identifiers

PMID34477562
PMCPMC8449302
OpenAlexW3198144000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.